Neurodegenerative disorders
Recent articles
Aging neurons outsource garbage disposal, clog microglia
Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.
Aging neurons outsource garbage disposal, clog microglia
Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.
Nonhuman primate research to lose federal funding at major European facility
The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.
Nonhuman primate research to lose federal funding at major European facility
The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.
New questions around motor neurons and plasticity
A researcher’s theory hangs muscle degeneration on a broken neural circuit.
New questions around motor neurons and plasticity
A researcher’s theory hangs muscle degeneration on a broken neural circuit.
Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease
To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.
Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease
To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.
The brain’s quiet conductor: How hidden cells fine-tune arousal
New research published today suggests that the pericoeruleus acts as a kind of micromanager of arousal, selectively inhibiting different subgroups of locus coeruleus neurons depending on the behavioral context.
The brain’s quiet conductor: How hidden cells fine-tune arousal
New research published today suggests that the pericoeruleus acts as a kind of micromanager of arousal, selectively inhibiting different subgroups of locus coeruleus neurons depending on the behavioral context.
In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.
In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Six new neuroscience books for fall—plus five titles you may have missed
We highlight the most anticipated neuroscience books for the remainder of 2024 and recap notable releases since last December.
Six new neuroscience books for fall—plus five titles you may have missed
We highlight the most anticipated neuroscience books for the remainder of 2024 and recap notable releases since last December.
Explore more from The Transmitter
Remembering Annette Dolphin, who helped explain gabapentin’s effects
The "intuitive" neuropharmacologist pushed against the status quo.
Remembering Annette Dolphin, who helped explain gabapentin’s effects
The "intuitive" neuropharmacologist pushed against the status quo.
Revised statistical bar extracts less-common variants from autism genetics studies
Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.
Revised statistical bar extracts less-common variants from autism genetics studies
Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.
Tom Griffiths describes how neural networks, logic and probability theory together explain cognition
In his new book, “The Laws of Thought,” Griffiths shows how these three pillars of study complement one another and together form a solid foundation to eventually explain all of our cognition, from brain to mind.
Tom Griffiths describes how neural networks, logic and probability theory together explain cognition
In his new book, “The Laws of Thought,” Griffiths shows how these three pillars of study complement one another and together form a solid foundation to eventually explain all of our cognition, from brain to mind.