Open neuroscience

A digitally distorted image of a file folder against a blue gradient background.

Data access changes to UK Biobank stir unease in neuroscientists

“I feel a little bit in limbo,” says neuroscientist Stephanie Noble, who has paused a study using Biobank data after the repository shifted from a data download to a cloud-only access model.

By Calli McMurray
16 July 2024 | 7 min read
Illustration of a scientist attempting to wrangle many forms of data at once: a pile of charts and graphs threatens to knock them off of their feet as they attempt to prop it up.

Neuroscience graduate students deserve comprehensive data-literacy education

Despite growing requirements around how to handle and share data, formal training is lacking.

By Letisha R. Wyatt
15 July 2024 | 6 min read

10 standards for brain electrode-array recordings enhance reproducibility

Electrophysiology findings can vary widely from lab to lab, even among those using identical protocols. New guidelines set forth in a preprint should help.

By Elissa Welle
12 July 2024 | 5 min read
A magnifying glass shines a light on a series of Xs.

Bounty hunting for blunders: Q&A with Russell Poldrack and Jan Wessel

The guinea pigs for a post-publication error-spotting project discuss why the field should destigmatize slipups—and how to handle them better.

By Calli McMurray
7 June 2024 | 10 min read
-A playful “cellular map” features top-down and bottom-up views of the human brain arranged side-by-side as if they were the earth’s two hemispheres in an old-fashioned map of the world. The brains are colored to suggest land masses and bodies of water.

Knowledge graphs can help make sense of the flood of cell-type data

These tools, widely used in the technology industry, could provide a foundation for the study of brain circuits.

By Michael Hawrylycz
28 May 2024 | 7 min read

Reporting bias widespread in early-childhood autism intervention trials

Only 7 percent of completed registered trials were later updated with results, one of several failings identified in a new analysis.

By Gina Jiménez
18 April 2024 | 5 min read
An abstract illustration of colorful lines on a yellow background

Pooling data points to new potential treatment for spinal cord injury

By gathering raw data from multiple labs, we identified an overlooked predictor of recovery after spinal cord injury. Many more insights remain trapped in scattered data.

By Adam Ferguson, Hannah Radabaugh, Abel Torres-Espin
4 March 2024 | 7 min read
An illustration of a diver assisting a scientist at a giant computer.

How scuba diving helped me embrace open science

Our lab adopted practices to make data- and code-sharing feel safer, including having the coding equivalent of a dive buddy. Trainees call the buddy system a welcome safety net.

By Ted Satterthwaite
19 February 2024 | 7 min read
Abstract illustration of antibodies scattered against a peach-colored background.

We found a major flaw in a scientific reagent used in thousands of neuroscience experiments — and we’re trying to fix it.

As part of that ambition, we launched a public-private partnership to systematically evaluate antibodies used to study neurological disease, and we plan to make all the data freely available.

By Mona AlQazzaz, Aled Edwards
5 February 2024 | 6 min read
Illustration of hands organizing objects of various shapes and sizes.

Simply making data publicly available isn’t enough. We need to make it easy — that requires community buy-in.

I helped create a standard to make it easy to upload, analyze and compare functional MRI data. An ecosystem of tools has since grown up around it, boosting reproducibility and speeding up research.

By Russell Poldrack
17 January 2024 | 7 min read

Explore more from The Transmitter

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read

Building an autism research registry: Q&A with Tony Charman

A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.

By Cathleen O’Grady
25 July 2024 | 8 min read

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read