Pain
Recent articles
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’
In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.

The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’
In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.
UBE3A’s link to synaptic pruning bolstered by fly study
Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.

UBE3A’s link to synaptic pruning bolstered by fly study
Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.
Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring
This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.

Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring
This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.
On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.

On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.
Pain keeps autistic women and girls home from work, school
More autistic women and girls report daily pain than do men and boys with the condition.

Pain keeps autistic women and girls home from work, school
More autistic women and girls report daily pain than do men and boys with the condition.
Epidurals linked to slightly higher autism odds, but connection is unclear
Women who receive epidural anesthesia during labor have an elevated chance of having a child with autism, a new study has found. But it is too soon for doctors to recommend against epidurals, experts say.

Epidurals linked to slightly higher autism odds, but connection is unclear
Women who receive epidural anesthesia during labor have an elevated chance of having a child with autism, a new study has found. But it is too soon for doctors to recommend against epidurals, experts say.
Autistic children disproportionately affected by chronic pain
Children with autism are about twice as likely as their typical peers to experience chronic or repeated pain.

Autistic children disproportionately affected by chronic pain
Children with autism are about twice as likely as their typical peers to experience chronic or repeated pain.
Explore more from The Transmitter
‘Digital humans’ in a virtual world
By combining large language models with modular cognitive control architecture, Robert Yang and his collaborators have built agents that are capable of grounded reasoning at a linguistic level. Striking collective behaviors have emerged.
‘Digital humans’ in a virtual world
By combining large language models with modular cognitive control architecture, Robert Yang and his collaborators have built agents that are capable of grounded reasoning at a linguistic level. Striking collective behaviors have emerged.
Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.

Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.
Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?