Pharmacology

Recent articles

Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.

Ketamine targets lateral habenula, setting off cascade of antidepressant effects

The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.

By Olivia Gieger
4 September 2024 | 6 min read
A photograph of a scientist holding a cannabis plant

Cannabis may be rescheduled–what does it mean for neuroscience?

The drug could become much easier to access, increasing the number of researchers who can work with it and the manufacturers who can produce it.

By Gina Jiménez
22 May 2024 | 5 min read
Black-and-white photograph of William Catterall in a lab.

The legacy of William Catterall, ‘father of ion channels’

Catterall, who characterized the structure, function and regulation of sodium and calcium channels crucial for neuronal excitability, died last month at the age of 77.

By Calli McMurray
12 March 2024 | 7 min read
Research images of the human motor cortex

What happens when a histopathologist teams up with computational modelers?

Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.

By Mac Shine
11 December 2023 | 7 min read

Explore more from The Transmitter

Clockwise: lab mouse, zebrafish, octopus, rat pushing a cube, nematodes, fruit fly.

The term ‘model organism’ should be reserved for biological systems

By referring to artificial neural networks as model organisms, we run the risk of distorting funding priorities and disregard the explanatory power of a shared evolutionary history across biological organisms.

By Marc Coutanche
13 November 2026 | 6 min read

New phase of BRAIN Initiative spawns basal ganglia ‘parts list’

With a standardized cell naming system and infrastructure for data collection and analysis, the basal ganglia project sets the stage for a whole-brain primate atlas.

By Claudia López Lloreda
12 November 2026 | 1 min watch
Research image showing genes containing microexons in mice.

Machine-learning model spots autism-linked variants that scramble splicing

The model provides a way to investigate genetic variation in regions of the genome whose functions have been difficult to interpret.

By Giorgia Guglielmi
12 November 2026 | 4 min read