Pharmacology

Recent articles

Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.

Ketamine targets lateral habenula, setting off cascade of antidepressant effects

The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.

By Olivia Gieger
4 September 2024 | 6 min read
A photograph of a scientist holding a cannabis plant

Cannabis may be rescheduled–what does it mean for neuroscience?

The drug could become much easier to access, increasing the number of researchers who can work with it and the manufacturers who can produce it.

By Gina Jiménez
22 May 2024 | 5 min read
Black-and-white photograph of William Catterall in a lab.

The legacy of William Catterall, ‘father of ion channels’

Catterall, who characterized the structure, function and regulation of sodium and calcium channels crucial for neuronal excitability, died last month at the age of 77.

By Calli McMurray
12 March 2024 | 7 min read
Research images of the human motor cortex

What happens when a histopathologist teams up with computational modelers?

Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.

By Mac Shine
11 December 2023 | 7 min read

Explore more from The Transmitter

Illustration of rolling dice.

Grant review needs reform. How about we add an element of chance?

A process that uses a lottery system saves time, reduces strategic resubmission and accepts that, above a quality threshold, luck has always played a part in science funding.

By Adrien Peyrache
25 September 2026 | 6 min read
Research diagram of gene expression.

Fly neurons carry molecular signatures of their origins

The pattern of transcription factors a Drosophila neuron expresses offers clues to its lineage and birth order—and ultimately how neural circuits emerge.

By Alissa de Chassey
25 September 2026 | 5 min read
Cortical organoids from the anterior (green) or posterior (red) cortex.

Polarized cortical organoids mimic the brain’s regional organization

The organoids show region-specific gene-expression changes that match those observed during fetal development.

By Holly Barker
24 September 2026 | 4 min read