Pharmacology

Recent articles

Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.

Ketamine targets lateral habenula, setting off cascade of antidepressant effects

The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.

By Olivia Gieger
4 September 2024 | 6 min read
A photograph of a scientist holding a cannabis plant

Cannabis may be rescheduled–what does it mean for neuroscience?

The drug could become much easier to access, increasing the number of researchers who can work with it and the manufacturers who can produce it.

By Gina Jiménez
22 May 2024 | 5 min read
Black-and-white photograph of William Catterall in a lab.

The legacy of William Catterall, ‘father of ion channels’

Catterall, who characterized the structure, function and regulation of sodium and calcium channels crucial for neuronal excitability, died last month at the age of 77.

By Calli McMurray
12 March 2024 | 7 min read
Research images of the human motor cortex

What happens when a histopathologist teams up with computational modelers?

Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.

By Mac Shine
11 December 2023 | 7 min read

Explore more from The Transmitter

Neuronal genes SATB2 and MEF2C.

Nuclear location helps control gene activity during brain development

A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.

By Giorgia Guglielmi
20 August 2026 | 4 min read
Cortical organoids.

Five-year-old human brain organoids aged on schedule

The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.

By Claudia López Lloreda
19 August 2026 | 5 min read