Plasticity

Recent articles

Eleanor Maguire.

Remembering Eleanor Maguire, ‘trailblazer’ of human memory

Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.

By Calli McMurray
10 January 2025 | 8 min read
Illustration of a mouse melting in front of a fan.

To beat the heat, hypothalamus neurons in mice ramp up their firing

The uptick may help the rodents acclimate to temperature hikes and keep their cool.

By Calli McMurray
11 December 2024 | 7 min read
Illustration of a pen hovering over a gene sequence-like series of colored rectangles.

This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab

This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.

By Anne E. West
27 November 2024 | 5 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
Illustration of a canyon landscape with an orange clock face in place of a sun.

How to teach this paper: ‘Behavioral time scale synaptic plasticity underlies CA1 place fields,’ by Bittner and Milstein et al. (2017)

Katie Bittner, Aaron Milstein and their colleagues found that cellular learning can happen over longer timescales than Hebb’s rule predicts. How long should we wait to teach students about this phenomenon?

By Ashley Juavinett
24 June 2024 | 11 min read
Illustrated portrait of Eve Marder

Eve Marder, neural circuits and being heard

The National Medal of Science winner explains why she built her career around the crustacean and what it was like attending high school in a Hudson River town.

By Brady Huggett
1 June 2024 | 79 min listen

The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’

In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.

By Moses V. Chao
26 April 2024 | 7 min read

Neurons making memories shush their neighbors

When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.

By Holly Barker
22 March 2024 | 5 min read
Photograph of a gloved hand pointing to a computer screen that is displaying an image of a mouse brain.

Going deep: The Transmitter’s top long-form stories in 2023

Our favorite features and book excerpts from the past year delved into the neurobiology of cancer; problems with survey data; free will; mathematical minds; and questions around one startup’s quest to treat brain conditions with cell therapies.

By The Transmitter
26 December 2023 | 4 min read
An abstract illustration of a figure from the shoulders up with multi-colored boxes on its face

What ‘drifting representations’ reveal about the brain

How neuronal activity patterns associated with a behavior can change, even when the behavior does not — something once seen as an experimental artifact — could offer new insights about neural function.

By Angie Voyles Askham
13 December 2023 | 8 min read

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David Krakauer reflects on the foundations and future of complexity science

In his book “The Complex World,” Krakauer explores how complexity science developed, from its early roots to the four pillars that now define it—entropy, evolution, dynamics and computation.

By Paul Middlebrooks
14 January 2025 | 106 min listen
Research image showing white matter volume in a child with Angelman syndrome compared with a child without the condition.

White-matter changes; lipids and neuronal migration; dementia

Here is a roundup of autism-related news and research spotted around the web for the week of 13 January.

By Jill Adams
14 January 2025 | 2 min read
Three sleeping mice.

Fleeting sleep interruptions may help brain reset

Brief, seconds-long microarousals during deep sleep “ride on the wave” of locus coeruleus activity in mice and correlate with periods of waste clearing and memory consolidation, new research suggests.

By Shaena Montanari
13 January 2025 | 5 min read