Plasticity

Illustration of a canyon landscape with an orange clock face in place of a sun.

How to teach this paper: ‘Behavioral time scale synaptic plasticity underlies CA1 place fields,’ by Bittner and Milstein et al. (2017)

Katie Bittner, Aaron Milstein and their colleagues found that cellular learning can happen over longer timescales than Hebb’s rule predicts. How long should we wait to teach students about this phenomenon?

By Ashley Juavinett
24 June 2024 | 11 min read
Illustrated portrait of Eve Marder
Synaptic Microphone

Eve Marder, neural circuits and being heard

The National Medal of Science winner explains why she built her career around the crustacean and what it was like attending high school in a Hudson River town.

By Brady Huggett
1 June 2024 | 79 min listen

The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’

In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.

By Moses V. Chao
26 April 2024 | 7 min read

Neurons making memories shush their neighbors

When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.

By Holly Barker
22 March 2024 | 5 min read
Photograph of a gloved hand pointing to a computer screen that is displaying an image of a mouse brain.

Going deep: The Transmitter’s top long-form stories in 2023

Our favorite features and book excerpts from the past year delved into the neurobiology of cancer; problems with survey data; free will; mathematical minds; and questions around one startup’s quest to treat brain conditions with cell therapies.

By The Transmitter
26 December 2023 | 4 min read
An abstract illustration of a figure from the shoulders up with multi-colored boxes on its face

What ‘drifting representations’ reveal about the brain

How neuronal activity patterns associated with a behavior can change, even when the behavior does not — something once seen as an experimental artifact — could offer new insights about neural function.

By Angie Voyles Askham
13 December 2023 | 8 min read
Close-up of a green glass slide embedded with dozens of tiny electrodes.
Neurobiology Microphone

Making cancer nervous

Nerve cells in the brain and throughout the body can turbocharge tumor growth — a finding that not only expands conventional ideas about the nervous system but points to novel therapeutic targets for a range of malignancies.

By Sarah DeWeerdt
13 November 2023 | 24 min listen

Explore more from The Transmitter

Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read

Building an autism research registry: Q&A with Tony Charman

A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.

By Cathleen O’Grady
25 July 2024 | 8 min read

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read