Sibling studies

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What baby siblings can teach us about autism

Studies of infants at risk for autism have not yielded a test to predict who will eventually be diagnosed. But they have transformed our understanding of the condition.

By Ingfei Chen
16 August 2017 | 18 min read
Spectrum stories podcast logo.

Spectrum Stories: Learning from baby siblings

Many parents with children on the spectrum enroll their newborns in research — to advance the field and to bring benefits to families such as theirs.

By Jacob Brogan
16 August 2017 | 1 min read

Parents’ interactions with infants may alleviate autism features

Teaching parents to respond to cues from babies at high risk of autism eases the severity of autism features at age 3.

By Bahar Gholipour
12 June 2017 | 4 min read

From the archives

Brain scans may forecast autism in high-risk infants

Patterns of brain activity in 6-month-old babies accurately predict which children will be diagnosed with autism at age 2.

By Nicholette Zeliadt
7 June 2017 | 5 min read

Excess brain fluid may forecast autism in babies

Some infants who are later diagnosed with autism have too much fluid between the brain and skull.

By Nicholette Zeliadt
6 March 2017 | 5 min read

The social network: How everyday interactions shape autism

A new study is the first rigorous test of a controversial idea: that the everyday interactions between caregiver and child can shape the course of autism.

By Nicholette Zeliadt
23 March 2015 | 12 min read

Lessons for parents may change autism’s trajectory

Coaching parents to provide early social stimulation may improve outcomes for children with autism.

By Geraldine Dawson
6 June 2017 | 8 min read

Questions for Ilina Singh: Ethics of ‘baby sib’ studies

Researchers are studying the infant siblings of children with autism, with hopes of improving the disorder’s diagnosis and treatment. They need to recognize the risks of these ‘baby sib’ studies, cautions ethicist Ilina Singh.

By Nicholette Zeliadt
14 July 2015 | 6 min read

Should scientists study mothers of children with autism?

Studying parents of children with autism has long been controversial, but that doesn’t mean scientists should avoid it.

By Helen Tager-Flusberg
12 April 2016 | 6 min read

Psychiatric problems common in siblings of people with autism

Mental health conditions crop up more than twice as often in families that include a child with autism as in the general population.

By Ann Griswold
23 June 2016 | 4 min read

Siblings of children with autism may show early setbacks

About 1 in 10 toddlers who have an older sibling with autism have cognitive and motor delays.

By Nicholette Zeliadt
31 August 2016 | 4 min read

Sensory abnormalities highlight early autism risk

Sensory abnormalities could be among the first signs of autism risk — and a target for early treatment.

By Sarah DeWeerdt
16 November 2016 | 3 min read

Survey for parents could flag autism in infants

Asking parents to fill out a questionnaire about their babies’ early skills could help clinicians spot signs of autism.

By Jessica Wright
13 February 2017 | 4 min read

Rapid brain growth in infancy may signal autism

The faster the brains of children with autism grow in their first year of life, the more severe their autism features are likely to be at age 2.

By Nicholette Zeliadt
15 February 2017 | 5 min read

Large study confirms high autism risk in ‘baby sibs’

Children who have an older sibling with autism are 14 times more likely to have the condition than are those without a family history of the condition.

By Ann Griswold
22 August 2016 | 4 min read

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Research image of four brain scans with green areas indicating Parasagittal dura volume.

Okur-Chung neurodevelopmental syndrome; excess CSF; autistic girls

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By Jill Adams
22 October 2024 | 2 min read
A collage illustration of a woman’s face fragmented by a mosaic of X chromosomes, lines and shapes.

Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research

New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.

By Rachel Buckley
22 October 2024 | 7 min read