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Bumetanide; sex-biased gene expression; racial and ethnic disparities

Here is a roundup of autism-related news and research spotted around the web for the week of 15 July.

By Jill Adams
16 July 2024 | 1 min read
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https://doi.org/10.53053/KYJH4430 https://doi.org/10.53053/KYJH4430 - opens a new tab Cite this article
  • A population-based assessment of conditions linked to recurrent copy number variants shows a lower likelihood of having autism, attention-deficit/hyperactivity disorder or schizophrenia than do previous estimates based on case-control studies. JAMA Psychiatry
  • Sex-biased gene expression in several regions of the rhesus monkey brain is regulated by sex hormones. Expression patterns are similar to those of humans. Cell Genomics
  • Parent-infant interactions—particularly the baby’s attentiveness to their parent—at ages 8 and 14 months appear to be predictive of autism diagnosis at 3 years. Autism Research
  • Bumetanide, a diuretic drug that blocks NKCC1 chloride transport proteins, mitigates the altered neuronal activity and sensory hypersensitivity that occurs in a mouse model of fragile X syndrome. Biological Psychiatry
  • Researchers returned results on a genetic analysis of autism-linked genes in a cohort of 21,532 autistic people. Genetic in Medicine
  • Autistic children are more likely than their non-autistic peers to have physical and mental health problems; those from minoritized racial and ethnic groups tend to have even poorer outcomes. Journal of Child and Adolescent Psychopharmacology

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