Synaptic pruning

Recent articles

Research image of the mouse dentate gyrus.

Microglia implicated in infantile amnesia

The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.

By Lauren Schneider
12 February 2026 | 5 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 5 min read
Two panels depict different brain wiring-like networks.

Rethinking how neural activity sculpts critical periods

New findings on the role of neural activity in developing circuits are challenging our prior notions about the rules that govern critical periods.

By Gregg Wildenberg
3 June 2025 | 5 min read
Research image of retinal ganglion cells in the lateral geniculate nucleus in mice.

Microglia’s pruning function called into question

Scientists are divided over the extent to which the cells sculpt circuits during development.

By RJ Mackenzie
24 October 2024 | 9 min read

Explore more from The Transmitter

Illustration of worm on top of a purple rock with neurons in the background.

The three-banded panther worm is rewriting the story of brain evolution

The animal has a brain structure all its own, according to a 2026 preprint. The finding hints that brains could have evolved centralization before regionalization.

By Sarah DeWeerdt
4 November 2026 | 7 min read

Does cognition happen in brain areas or between them?

Michael Cole explains how "brain flows" are the fundamental units of brain function and cognition.

By Paul Middlebrooks
4 November 2026 | 1 min read
Brain Flows book cover

‘Brain Flows: How Network Dynamics Compose the Human Mind,’ an excerpt

In his new book, published today, Michael W. Cole examines how the movement of neuronal activity between neuronal populations shapes free will, intelligence and creativity. In this excerpt from Chapter 1, Cole explores why activity flows could unify efforts to map brain functions and connectivity.

By Michael W. Cole
3 November 2026 | 9 min read