Synaptic pruning

Recent articles

Research image of the mouse dentate gyrus.

Microglia implicated in infantile amnesia

The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.

By Lauren Schneider
12 February 2026 | 5 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 5 min read
Two panels depict different brain wiring-like networks.

Rethinking how neural activity sculpts critical periods

New findings on the role of neural activity in developing circuits are challenging our prior notions about the rules that govern critical periods.

By Gregg Wildenberg
3 June 2025 | 5 min read
Research image of retinal ganglion cells in the lateral geniculate nucleus in mice.

Microglia’s pruning function called into question

Scientists are divided over the extent to which the cells sculpt circuits during development.

By RJ Mackenzie
24 October 2024 | 9 min read

Explore more from The Transmitter

Stock photo of a group of neurons.

Finding neuroheterogeneity’s sweet spot

Once thought to be detrimental to memory processing, neuronal diversity—at the right ‘Goldilocks’ dose—is a new boon to theoretical neuroscience.

By Natalia Mesa
20 October 2026 | 7 min read
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

COVID-19 and influenza effects in pregnancy; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 19 October.

By Jill Adams
20 October 2026 | 2 min read
Illustration of a person standing in a crumbling room with papers and strings on the wall, a fallen chair, and a lamp.

What to do when traditional mechanistic approaches no longer work

Many complex behaviors have stubbornly resisted mechanistic explanations. Deciphering them will require new approaches—and perhaps a new concept of “understanding.”

By Bence Ölveczky
19 October 2026 | 8 min read