Synaptic pruning

Recent articles

Two panels depict different brain wiring-like networks.

Rethinking how neural activity sculpts critical periods

New findings on the role of neural activity in developing circuits are challenging our prior notions about the rules that govern critical periods.

By Gregg Wildenberg
3 June 2025 | 5 min read
Research image of retinal ganglion cells in the lateral geniculate nucleus in mice.

Microglia’s pruning function called into question

Scientists are divided over the extent to which the cells sculpt circuits during development.

By RJ Mackenzie
24 October 2024 | 9 min read

Explore more from The Transmitter

Neurons in cerebral organoids containing a MECP2 variant (right panel) have smaller cell bodies and fewer branches than those in wildtype organoids (left panel).

Autism in Kenya, organoid research, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 22 December.

By Jill Adams
23 December 2025 | 2 min read
Research image of the human dorsal root ganglion.

‘Unprecedented’ dorsal root ganglion atlas captures 22 types of human sensory neurons

The atlas also offers up molecular and cellular targets for new pain therapies.

By Calli McMurray
23 December 2025 | 5 min read
Illustration of a simple circuit.

Not playing around: Why neuroscience needs toy models

Amid the rise of billion-parameter models, I argue that toy models, with just a few neurons, remain essential—and may be all neuroscience needs.

By Marcus Ghosh
22 December 2025 | 6 min read

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