Synaptic pruning

Recent articles

Research image of the mouse dentate gyrus.

Microglia implicated in infantile amnesia

The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.

By Lauren Schneider
12 February 2026 | 5 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 5 min read
Two panels depict different brain wiring-like networks.

Rethinking how neural activity sculpts critical periods

New findings on the role of neural activity in developing circuits are challenging our prior notions about the rules that govern critical periods.

By Gregg Wildenberg
3 June 2025 | 5 min read
Research image of retinal ganglion cells in the lateral geniculate nucleus in mice.

Microglia’s pruning function called into question

Scientists are divided over the extent to which the cells sculpt circuits during development.

By RJ Mackenzie
24 October 2024 | 9 min read

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Post-infection immune conflict alters fetal development in some male mice

The immune-conflict between dam and fetus could help explain sex differences in neurodevelopmental conditions.

By Viviane Callier
26 February 2026 | 5 min read

Three ecological psychologists on the right and wrong ways to use the field’s principles in neuroscience

Matthieu de Wit, Luis H. Favela and Vicente Raja weigh in on the recent trend of neuroscientists importing concepts from ecological psychology, the study of how an organism’s interactions with its environment explain perception and action.

By Paul Middlebrooks
25 February 2026 | 1 min read
Sam Wang.

Is there a neuroscientist in the House?

Sam Wang, a neuroscientist running for the U.S. House of Representatives, has been considering American democracy for decades.

By Lauren Schenkman
25 February 2026 | 7 min read

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