Theories of autism
Recent articles
The signaling imbalance theory of autism, explained
The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.
The signaling imbalance theory of autism, explained
The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.
The female protective effect, explained
One of the leading theories of autism posits that girls and women are biologically protected from the condition.
The female protective effect, explained
One of the leading theories of autism posits that girls and women are biologically protected from the condition.
The extreme male brain, explained
The ‘extreme male brain’ theory suggests that autism is an exaggeration of systematic sex differences in ways of thinking.
The extreme male brain, explained
The ‘extreme male brain’ theory suggests that autism is an exaggeration of systematic sex differences in ways of thinking.
Serotonin’s link to autism, explained
Serotonin, the brain chemical best known for its link to depression, may also be involved in autism.
Serotonin’s link to autism, explained
Serotonin, the brain chemical best known for its link to depression, may also be involved in autism.
The multiple hits theory of autism, explained
Researchers are studying how a combination of genetic ‘hits’ may contribute to autism’s diversity.
The multiple hits theory of autism, explained
Researchers are studying how a combination of genetic ‘hits’ may contribute to autism’s diversity.
The predictive coding theory of autism, explained
In autism, a person's brain may not form accurate predictions of imminent experiences, or even if it does, sensory input may override those predictions.
The predictive coding theory of autism, explained
In autism, a person's brain may not form accurate predictions of imminent experiences, or even if it does, sensory input may override those predictions.
The connectivity theory of autism, explained
A growing body of evidence suggests that autism involves atypical communication between brain regions, but how and where in the brain this plays out is unclear.
The connectivity theory of autism, explained
A growing body of evidence suggests that autism involves atypical communication between brain regions, but how and where in the brain this plays out is unclear.
Explore more from The Transmitter
‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
Reporter’s notebook: Highlights from INSAR 2025
The annual meeting brought autism researchers, advocates and clinicians to Seattle to discuss the latest research, including attempts to define subgroups, a potential new CHD8 macaque model and life expectancy gaps.
Reporter’s notebook: Highlights from INSAR 2025
The annual meeting brought autism researchers, advocates and clinicians to Seattle to discuss the latest research, including attempts to define subgroups, a potential new CHD8 macaque model and life expectancy gaps.
NIDA shutters diversity fellowship program, axes active awards
It’s unclear if the cancellation at the U.S. National Institute on Drug Abuse extends to the fellowships awarded by other institutes within the National Institutes of Health.
NIDA shutters diversity fellowship program, axes active awards
It’s unclear if the cancellation at the U.S. National Institute on Drug Abuse extends to the fellowships awarded by other institutes within the National Institutes of Health.