Treatments

Recent articles

Illustration of clinicians, a pill bottle, a speech bubble and shadowy figures.

Neuroscientists need to do better at explaining basic mental health research

The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.

By Omar Abubaker, Karla Kaun, Eric J. Nestler
21 January 2025 | 7 min read
Photograph of a syringe.

What’s next for brain-directed gene therapy after death in Neurogene trial

The incident highlights that viral vectors can trigger deadly immune responses even when delivered directly to the nervous system.

By Calli McMurray
26 November 2024 | 6 min read
Two rhesus macaque monkeys.

Vasopressin boosts sociability in solitary monkeys

Inhaling the hormone did not increase aggression in unsociable rhesus macaques and appears to help the animals remember faces and reciprocate friendly behaviors.

By Charles Q. Choi
25 November 2024 | 5 min read
Research image of toxoplasma gondii showing cysts it creates as well as the MECP2 protein that it can deliver to neurons.

Parasite-based tool delivers MECP2 and other proteins to neurons

A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.

By Giorgia Guglielmi
12 September 2024 | 4 min read
Stock photograph of a women and her young child at a clinician’s office.

A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman

A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.

By Lauren Schenkman
15 August 2024 | 7 min read
A hand holds a stack of speech bubbles.

Leveraging the power of community to strengthen clinical trials for rare genetic syndromes

Families can become not only participants but champions of these research efforts.

By Shafali Spurling Jeste
11 July 2024 | 7 min read
Research image of neurons in a small section of the hippocampus.

Tail of hippocampus may be hub for seizures in mice and people

This little-studied subregion, called the fasciola cinereum, could be a new surgical target for people with treatment-resistant epilepsy.

By Shaena Montanari
14 June 2024 | 4 min read
Portrait of Matthew Siegel sitting on a staircase.

Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel

A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.

By Katie Moisse
13 June 2024 | 7 min read
Research image of two fluorescent-stained organoids.

CRISPR gives autism-linked genes a boost, rescues functioning

A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.

By Giorgia Guglielmi
23 May 2024 | 5 min read
Research image of antisense oligonucleotides.

RNA drug corrects calcium signaling in chimeric model of Timothy syndrome

The drug, tested in rats that have human neurons, could enter clinical testing as early as next year, researchers say.

By Katie Moisse
24 April 2024 | 5 min read

Explore more from The Transmitter

Research image of brain organoids with astroglia formation represented in green.

Personalized medicine; astroglia organoids; fast track for fragile X drug

Here is a roundup of autism-related news and research spotted around the web for the week of 20 January.

By Jill Adams
21 January 2025 | 2 min read
Grid of human brain scans.

Dose, scan, repeat: Tracking the neurological effects of oral contraceptives

We know little about how the brain responds to oral contraceptives, despite their widespread use. I am committed to changing that: I scanned my brain 75 times over the course of a year and plan to make my data openly available.

By Carina Heller
20 January 2025 | 7 min read
Colorful illustration of a latticework of proteins.

Cracking the code of the extracellular matrix

Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.

By Anna Victoria Molofsky
17 January 2025 | 5 min read