Treatments
Recent articles
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.
Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.
Neuroscientists need to do better at explaining basic mental health research
The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.
Neuroscientists need to do better at explaining basic mental health research
The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.
What’s next for brain-directed gene therapy after death in Neurogene trial
The incident highlights that viral vectors can trigger deadly immune responses even when delivered directly to the nervous system.
What’s next for brain-directed gene therapy after death in Neurogene trial
The incident highlights that viral vectors can trigger deadly immune responses even when delivered directly to the nervous system.
Vasopressin boosts sociability in solitary monkeys
Inhaling the hormone did not increase aggression in unsociable rhesus macaques and appears to help the animals remember faces and reciprocate friendly behaviors.
Vasopressin boosts sociability in solitary monkeys
Inhaling the hormone did not increase aggression in unsociable rhesus macaques and appears to help the animals remember faces and reciprocate friendly behaviors.
Parasite-based tool delivers MECP2 and other proteins to neurons
A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.
Parasite-based tool delivers MECP2 and other proteins to neurons
A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
Leveraging the power of community to strengthen clinical trials for rare genetic syndromes
Families can become not only participants but champions of these research efforts.
Leveraging the power of community to strengthen clinical trials for rare genetic syndromes
Families can become not only participants but champions of these research efforts.
Tail of hippocampus may be hub for seizures in mice and people
This little-studied subregion, called the fasciola cinereum, could be a new surgical target for people with treatment-resistant epilepsy.
Tail of hippocampus may be hub for seizures in mice and people
This little-studied subregion, called the fasciola cinereum, could be a new surgical target for people with treatment-resistant epilepsy.
Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel
A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.
Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel
A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.
Explore more from The Transmitter
Mitochondrial ‘landscape’ shifts across human brain
Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.
Mitochondrial ‘landscape’ shifts across human brain
Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
Dean Buonomano explores the concept of time in neuroscience and physics
He outlines why he thinks integrated information theory is unscientific and discusses how timing is a fundamental computation in brains.
Dean Buonomano explores the concept of time in neuroscience and physics
He outlines why he thinks integrated information theory is unscientific and discusses how timing is a fundamental computation in brains.