Animal models

Recent articles

Cell ‘antennae’ link autism, congenital heart disease

Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.

By Lauren Schenkman
24 July 2025 | 4 min listen
Different colored rectangles form the shapes of a bird, fish and insect.

Systems and circuit neuroscience need an evolutionary perspective

To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.

By Karl Farrow, Katja Reinhard
16 July 2025 | 7 min listen
Researcher holds a mouse perched on a glass cylinder.

NIH proposal sows concerns over future of animal research, unnecessary costs

The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.

By Claudia López Lloreda
15 July 2025 | 6 min listen
A fly over a background of waves of different colors.

Drosophila, like vertebrates, filter sensory information during sleep

Predictive sensory processing in sleeping Drosophila echoes vertebrate research, establishing an evolutionarily conserved neural signature of sleep.

By Siddhant Pusdekar
8 July 2025 | 5 min listen
Research image of excitatory neurons in the mouse hippocampus.

Spatial learning circuitry fluctuates in step with estrous cycle in mice

Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.

By Sydney Wyatt
25 June 2025 | 6 min listen
Photograph of a moth.

Star-responsive neurons steer moths’ long-distance migration

Cells in the bogong moth brain respond to astral landmarks to orient the insects in the direction they need to go.

By Angie Voyles Askham
18 June 2025 | 5 min listen
Research image of neurons in the interpeduncular nucleus.

‘Understudied secret’ in brain dampens nicotine drive in mice

The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

By Lauren Schenkman
4 June 2025 | 5 min listen

Escaping groupthink: What animals’ behavioral quirks reveal about the brain

Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.

By Angie Voyles Askham
23 May 2025 | 10 min listen
Tic-tac-toe board with pills representing x’s and o’s.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté

Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

By Sydney Wyatt
18 April 2025 | 7 min read
Research image of grids of mouse and human brain scans.

Too much or too little brain synchrony may underlie autism subtypes

Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

By Calli McMurray
17 April 2025 | 6 min read

Explore more from The Transmitter

Research visualization of reverberating activity in a selection of higher-order brain areas.

Eye puffs prompt separable sensory, affective brain responses in mice, people

Post-puff brain state might not be an emotion, some researchers caution, but the protocol provides a cross-species approach to study emotions.

By Calli McMurray
29 July 2025 | 8 min listen
Research image of dendrites in mice.

Probing the link between preterm birth and autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 28 July.

By Jill Adams
29 July 2025 | 2 min read
Brain scans showing activity in areas associated with threat detection and peripersonal space.

Human brain may anticipate looming contagion

Seeing a visibly ill avatar in virtual reality activates a neuroimmune pathway in brain areas related to peripersonal space and prompts an immune response, a small new study suggests.

By Claudia López Lloreda
28 July 2025 | 6 min read