Circuits
Recent articles
How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
Escaping groupthink: What animals’ behavioral quirks reveal about the brain
Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.
Escaping groupthink: What animals’ behavioral quirks reveal about the brain
Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.
Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.

Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.
Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Soft touch quells loneliness in mice
Touch modulates one of two dueling types of hypothalamic neurons that, thermostat-like, balance an animal’s drive for social interaction.

Soft touch quells loneliness in mice
Touch modulates one of two dueling types of hypothalamic neurons that, thermostat-like, balance an animal’s drive for social interaction.
Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.

Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.
Assembloids illuminate circuit-level changes linked to autism, neurodevelopment
These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.
Assembloids illuminate circuit-level changes linked to autism, neurodevelopment
These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.
START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.
Explore more from The Transmitter
On the importance of reading (just not too much)
The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.

On the importance of reading (just not too much)
The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.
NIH autism database announcement raises concerns among researchers
The U.S. National Institutes of Health announced a plan to pour $50 million into data science projects intended to investigate the condition’s causes, but the initiative’s short timeline and other atypicalities have prompted questions.

NIH autism database announcement raises concerns among researchers
The U.S. National Institutes of Health announced a plan to pour $50 million into data science projects intended to investigate the condition’s causes, but the initiative’s short timeline and other atypicalities have prompted questions.
Large study links autism to Parkinson’s disease
Autistic adults appear to be prone to an early-onset form of Parkinson’s, according to a long-term study that tracked 2.2 million people in Sweden.

Large study links autism to Parkinson’s disease
Autistic adults appear to be prone to an early-onset form of Parkinson’s, according to a long-term study that tracked 2.2 million people in Sweden.