Connectivity
Recent articles
Local circuit loops within body control fly behavior, new ‘embodied’ connectome reveals
The mapping, which traces how the central nervous system interacts with the rest of the body, challenges the idea that behavior control is centralized.

Local circuit loops within body control fly behavior, new ‘embodied’ connectome reveals
The mapping, which traces how the central nervous system interacts with the rest of the body, challenges the idea that behavior control is centralized.
Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.

Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.
Longer fMRI brain scans boost reliability—but only to a point
Around 30 minutes of imaging per person seems to be the “sweet spot” for linking functional connectivity differences to traits in an accurate and cost-effective way.

Longer fMRI brain scans boost reliability—but only to a point
Around 30 minutes of imaging per person seems to be the “sweet spot” for linking functional connectivity differences to traits in an accurate and cost-effective way.
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.

Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.
Too much or too little brain synchrony may underlie autism subtypes
Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

Too much or too little brain synchrony may underlie autism subtypes
Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.

Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.
Explore more from The Transmitter
Neurons fuel lung tumors that have spread to brain
Functional synapses between brain cells and cancer cells are key to the metastatic growth, according to new findings from two independent teams.

Neurons fuel lung tumors that have spread to brain
Functional synapses between brain cells and cancer cells are key to the metastatic growth, according to new findings from two independent teams.
Meet the Autism Data Science Initiative grantees
The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.

Meet the Autism Data Science Initiative grantees
The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.
Exclusive: The 23 studies the FDA based its expanded leucovorin label on
The studies include 46 people, mostly toddlers, who have cerebral folate deficiency due to variants in a folate transporter.

Exclusive: The 23 studies the FDA based its expanded leucovorin label on
The studies include 46 people, mostly toddlers, who have cerebral folate deficiency due to variants in a folate transporter.