Connectivity
Recent articles
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

‘Ancient’ brainstem structure evolved beyond basic motor control
The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.
Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.

Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.
Too much or too little brain synchrony may underlie autism subtypes
Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

Too much or too little brain synchrony may underlie autism subtypes
Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.

Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.
START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
New ‘decoder’ tool translates functional neuroimaging terms across labs
The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.

New ‘decoder’ tool translates functional neuroimaging terms across labs
The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.
Explore more from The Transmitter
Gazing at a location from afar activates place cells in chickadees
The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.

Gazing at a location from afar activates place cells in chickadees
The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.
Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind
Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.

Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind
Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.
Psychedelics meta-analysis retracted after authors request ‘significant changes’
While working on a similar analysis last year, an independent researcher spotted inconsistencies in the now-retracted paper.

Psychedelics meta-analysis retracted after authors request ‘significant changes’
While working on a similar analysis last year, an independent researcher spotted inconsistencies in the now-retracted paper.