Monkeys for autism research

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Spectrum from The Transmitter.

The treasures of monkey island

On Cayo Santiago island, scientists track the alliances and power struggles of a colony of feral monkeys — collecting data to generate new insights into the social challenges that people with autism face.

By Brendan Borrell
22 June 2016 | 23 min read
Spectrum from The Transmitter.

Genetically modified monkeys show autism-like behaviors

Monkeys with multiple copies of a gene called MeCP2 show behaviors reminiscent of autism, but some experts question the model’s value.

By Nicholette Zeliadt
27 January 2016 | 6 min read
Spectrum from The Transmitter.

Questions for Cory Miller: Monkeying around with marmosets

Small social monkeys called marmosets are well suited for studies on social behaviors and autism.

By Nicholette Zeliadt
10 May 2016 | 5 min read

From the archives

Spectrum from The Transmitter.

Questions for Karen Parker: Probing monkey social behavior

Like people, monkeys vary widely in their social abilities. Behavioral neuroscientist Karen Parker explains how studying social behavior in monkeys can advance how we understand and treat autism.

By Nicholette Zeliadt
4 November 2014 | 6 min read
Spectrum from The Transmitter.

Monkey mother’s immune response changes her infant’s brain

Monkeys whose mothers are infected with a mock virus while pregnant show abnormal branching of certain brain cells. The findings may help explain why infection during a woman’s pregnancy ups the risk of autism in her children.

By Charles Q. Choi
27 April 2015 | 3 min read
Spectrum from The Transmitter.

New tool offers way to ‘light up’ cells in monkey brain

A new technique can stimulate and record activity across broad swaths of the monkey brain.

By Ann Griswold
16 March 2016 | 3 min read
Spectrum from The Transmitter.

Atlas charts gene activity in developing monkey brains

Researchers have for the first time mapped gene expression in the rhesus macaque brain from birth through adulthood. The atlas illuminates the expression patterns of genes likely to be important in autism.

By Kate Yandell
10 June 2015 | 3 min read
Spectrum from The Transmitter.

Marmosets that miss social cues may mimic autism

Marmosets exposed to an epilepsy drug in the womb do not recognize reciprocity — the social give-and-take that is a challenge for some people with autism — suggests a new study. The findings add to mounting evidence that these tiny monkeys offer clues about autism.

By Kate Yandell
29 July 2015 | 3 min read
Spectrum from The Transmitter.

Video technique measures monkeys’ social interest

Male rhesus macaques show more interest in videos with social content, such as another monkey displaying aggression, than in videos of landscapes or other animals, according to a study published 26 October in PLoS One.

By Jessica Wright
11 January 2012 | 3 min read
Spectrum from The Transmitter.

Engineered monkeys carry autism-linked mutations

Researchers have created the first genetic monkey model of autism, they reported 6 March in Cell Stem Cell. The female monkey has a mutated version of the MeCP2 gene that causes Rett syndrome.

By Jessica Wright
9 April 2014 | 2 min read
Spectrum from The Transmitter.

Neurons move early, mature late in developing monkey brain

Researchers have mapped the migration patterns of neurons in the developing monkey brain and pinpointed when they establish their identities.

By Katie Moisse
19 October 2015 | 3 min read
Spectrum from The Transmitter.

Social hormone may lead to solo outlook in monkey brains

Contrary to its reputation, oxytocin may make monkeys less interested in others’ actions and more focused on their own.

By Jessica Wright
19 October 2015 | 4 min read
Spectrum from The Transmitter.

Monkey models march into autism research arena

Overcoming profound technical challenges, researchers may be well on their way to making a troop of monkey models for studying autism and related conditions

By Jessica Wright
21 October 2015 | 4 min read
Spectrum from The Transmitter.

On monkey island, some animals carry autism-linked mutation

Roughly one-sixth of the monkeys on an island off the coast of Puerto Rico may carry a variant in SHANK3, a top autism gene candidate.

By Jessica Wright
20 October 2015 | 4 min read
Spectrum from The Transmitter.

Researchers flag targets of autism-linked antibodies

Two studies published 9 July bolster the hypothesis that immune molecules in a pregnant woman’s bloodstream may sometimes cause autism in her child.

By Sarah DeWeerdt
25 July 2013 | 7 min read
Spectrum from The Transmitter.

Mother’s immune response triggers odd behavior in monkeys

Triggering immune defenses in pregnant monkeys can lead to repetitive behaviors and social problems in their babies, according to a study published 4 September in Biological Psychiatry.

By Jessa Netting
7 October 2013 | 4 min read
Spectrum from The Transmitter.

Video: What monkeys can teach us about autism

Earl Miller tells SFARI.org how monkeys inspired his theory for the cognitive deficits in autism.

By Jessica Wright
12 November 2011 | 2 min read

Explore more from The Transmitter

Research image of neuron organization in c elegans.

Worms help untangle brain structure/function mystery

The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans

By Holly Barker
29 August 2025 | 7 min read
Research image of microglia in organoids.

Microglia nurture young interneurons

The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”

By Lauren Schenkman
28 August 2025 | 4 min read

Xaq Pitkow shares his principles for studying cognition in our imperfect brains and bodies

Pitkow discusses how evolution's messy constraints shape optimal brain algorithms, from Bayesian inference to ecological affordances.

By Paul Middlebrooks
27 August 2025 | 1 min read

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