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The latest developments in neuroscience

Memory astrocytes.

Null and Noteworthy: Reanalysis contradicts report of immune memory in astrocytes

The analysis, which has not yet been peer reviewed, attributes the finding to misidentified immune cells instead.

By Laura Dattaro
30 April 2025 | 5 min read
Research image of neural progenitor cells.

Documenting decades of autism prevalence; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 28 April.

By Jill Adams
29 April 2025 | 1 min read

‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures

The tool provides a new way to characterize cells and study neuronal circuits.

By Claudia López Lloreda
29 April 2025 | 4 min read
Pixelated human brain scans showing the distribution of mitochondria.

Mitochondrial ‘landscape’ shifts across human brain

Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.

By Claudia López Lloreda
25 April 2025 | 6 min read
A clinician holds a clipboard while someone else sits on a couch.

Expediting clinical trials for profound autism: Q&A with Matthew State

Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.

By Lauren Schenkman
24 April 2025 | 8 min read
Figure showing sleep archetypes in autistic children.

Rise in autism prevalence; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 21 April.

By Jill Adams
22 April 2025 | 2 min read
Research image of fMRI scans showing decision-making across individuals.

During decision-making, brain shows multiple distinct subtypes of activity

Person-to-person variability in brain activity might represent meaningful differences in cognitive processes, rather than random noise.

By Claudia López Lloreda
18 April 2025 | 5 min read
Tic-tac-toe board with pills representing x’s and o’s.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté

Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

By Sydney Wyatt
18 April 2025 | 7 min read
NIH building cut by a red line, a section of the building falls out of the frame.

Proposed NIH budget cut threatens ‘massive destruction of American science’

A leaked draft of a Trump administration proposal includes an approximately 40 percent cut to the National Institutes of Health’s budget and a major reorganization of its 27 institutes and centers.

By Angie Voyles Askham
17 April 2025 | 3 min read
Research image of grids of mouse and human brain scans.

Too much or too little brain synchrony may underlie autism subtypes

Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

By Calli McMurray
17 April 2025 | 6 min read

Explore more from The Transmitter

Federal funding cuts imperil next generation of autism researchers

As the International Society for Autism Research’s annual meeting begins, its next president reflects on a brewing crisis.

By Brian Boyd
30 April 2025 | 5 min read
Mock-up of the Neuropixels probe inserted into brain tissue.

Tracking single neurons in the human brain reveals new insight into language and other human-specific functions

Better technologies to stably monitor cell populations over long periods of time make it possible to study neural coding and dynamics in the human brain.

By Edward Chang, Jason Chung
28 April 2025 | 7 min read
Illustration of astrocytes in a petri dish.

This paper changed my life: Shane Liddelow on two papers that upended astrocyte research

A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

By Shane Liddelow
23 April 2025 | 6 min read