Theoretical neuroscience

Recent articles

A blue 3D cube made of interlacing smooth, round tubes.

Thinking about thinking: AI offers theoretical insights into human memory

We need a new conceptual framework for understanding cognitive functions—particularly how globally distributed brain states are formed and maintained for hours.

By Terrence Sejnowski
5 May 2025 | 8 min listen
Two scientists walk along interlocking rings.

Breaking the barrier between theorists and experimentalists

Many neuroscience students are steeped in an experiment-first style of thinking that leads to “random walk science.” Let’s not forget how theory can guide experiments toward deeper insights.

By Samuel Gershman
24 February 2025 | 6 min read
Futuristic illustration of overlapping circles and bright dots.

Future watch: What should neuroscience prioritize during the next 10 to 20 years?

For The Transmitter’s first annual book, five contributing editors reflect on what subfields demand greater focus in the near future—from dynamical systems and computation to technologies for studying the human brain.

By The Transmitter
23 December 2024 | 1 min read
High-resolution image of interconnected brain cells highlighted in magenta and blue.

What are recurrent networks doing in the brain?

The cortex is filled with excitatory local synapses, but we know little about their role in brain function. New experimental tools, along with ideas from artificial intelligence, are poised to change that.

By Mark Histed
16 December 2024 | 5 min read
Illustration of a fly with its life cycle represented on its left and a technological background on its right.

Computational and systems neuroscience needs development

Embracing recent advances in developmental biology can drive a new wave of innovation.

By Ben Scott
2 July 2024 | 6 min read
Abstract illustration of paper shapes representing different kinds of ideas and speech.

Must a theory be falsifiable to contribute to good science?

Four researchers debate the role that non-testable theories play in neuroscience.

By Grace Lindsay, moderator
10 June 2024 | 55 min read

Explore more from The Transmitter

On the importance of reading (just not too much)

The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.

By Sheena Josselyn
9 June 2025 | 8 min read
Research image of developing axons in the fly brain.

How developing neurons simplify their search for a synaptic mate

Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

By Calli McMurray
6 June 2025 | 6 min read
Distorted floppy discs.

NIH autism database announcement raises concerns among researchers

The U.S. National Institutes of Health announced a plan to pour $50 million into data science projects intended to investigate the condition’s causes, but the initiative’s short timeline and other atypicalities have prompted questions.

By Angie Voyles Askham
5 June 2025 | 5 min read