Connectome

Recent articles

Long-sought walking circuit found in fruit flies

The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.

By Natalia Mesa
13 May 2026 | 0 min watch
Research image of lesion network mapping.

‘Overdue’ debate unfurls over neuroimaging method

After a January paper questioned the validity of an approach called lesion network mapping, its users are pressure testing their results.

By Angie Voyles Askham
17 April 2026 | 8 min read
Digital model of a fly next to a digital model of a nematode.

‘Digital sphinx’ raises questions about connectome models

The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.

By Natalia Mesa
2 April 2026 | 5 min read
Researcher Russell Poldrack's face closeup, with a scanner seen out of focus behind him.

A brief history of precision self-scanning

When a researcher solved a logistical problem by going rogue, the idea proved remarkably infectious.

By Lauren Gravitz
21 January 2026 | 13 min read
Brain network maps creating using lesion network mapping.

Methodological flaw may upend network mapping tool

The lesion network mapping method, used to identify disease-specific brain networks for clinical stimulation, produces a nearly identical network map for any given condition, according to a new study.

By Angie Voyles Askham
15 January 2026 | 7 min read

Can neuroscientists decode memories solely from a map of synaptic connections?

Five experts discuss the progress, possibilities and hurdles of decoding a “nontrivial” memory from an organism just by analyzing its brain connectivity patterns.

By Paul Middlebrooks
17 December 2025 | 1 min read
A man with glasses reads from a paper with a graph-like pattern of peaks and valleys on it.

The buzziest neuroscience papers of 2023, 2024

The field took note of work on brain-computer interfaces for speech, the mechanism of psychedelics, a broader definition of hippocampal representations, and more.

By Calli McMurray, Francisco J. Rivera Rosario
15 November 2025 | 18 min read
A worm made of circuitry.

Whole-brain, bottom-up neuroscience: The time for it is now

Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.

By Edward Boyden, Konrad Körding
20 October 2025 | 9 min read
A drosophila connectome.

One year of FlyWire: How the resource is redefining Drosophila research

We asked nine neuroscientists how they are using FlyWire data in their labs, how the connectome has transformed the field and what new tools they would like to see in the future.

By Francisco J. Rivera Rosario
7 October 2025 | 17 min read
Map of the fly nervous system.

Local circuit loops within body control fly behavior, new ‘embodied’ connectome reveals

The mapping, which traces how the central nervous system interacts with the rest of the body, challenges the idea that behavior control is centralized.

By Claudia López Lloreda
24 September 2025 | 5 min read

Explore more from The Transmitter

Research image of inputs into a single neuron in the mouse visual cortex

‘Unbelievably beautiful’ evidence extends Nobel Prize-winning model of vision

Orientation tuning—the ability to distinguish a horizontal line from a vertical one or something in between—originates in the visual cortex, according to new mouse synapse imaging experiments.

By Claudia López Lloreda
29 May 2026 | 5 min read
Illustration of people connecting basic science.

Bringing basic biology back to INSAR

As the International Society for Autism Research has grown over the past two decades, basic science has become less central, Christine Wu Nordahl says. This year, she and other meeting organizers aimed to change that.

By Diana Kwon
28 May 2026 | 6 min read
Illustration of scale balancing Petri dish and test tubes.

Every neuroscience lab needs an ethicist

The ethics issues that arise in neuroscience research are usually novel, unresolved and understudied. Embedding ethicists in labs helps scientists navigate these challenges and develop strategies in real time to prevent harm.

By Timothy E. Brown
27 May 2026 | 5 min read