Michele Solis is a freelance writer based in Seattle, Washington.
Michele Solis
Freelance Writer
SFARI
From this contributor
Molecular mechanisms: Autism protein connects neurons
An autism-linked protein called CASPR2 promotes the development of dendrites, the bushy structures atop neurons that receive signals from other neurons, according to a study published 30 October in Proceedings of the National Academy of Sciences. Lowering CASPR2 levels leads to sparse dendrites and few synapses, the junctions between neurons.

Molecular mechanisms: Autism protein connects neurons
Molecular mechanisms: Stress pathway dysregulated in autism
Two studies report abnormalities in the system that mediates the body’s response to stress in two mouse models of autism-related diseases: Angelman syndrome and Rett syndrome. The results were published in the April issue of Human Molecular Genetics.

Molecular mechanisms: Stress pathway dysregulated in autism
Molecular mechanisms: Autism gene tied to neuronal wiring
An autism-linked protein helps wire neurons together, according to two studies published in late September.

Molecular mechanisms: Autism gene tied to neuronal wiring
Molecular mechanisms: MeCP2 loss ups signal strength
A study using action potentials, the electrical impulses that trigger signaling, shows that neurons lacking MeCP2, the Rett syndrome protein, have stronger neuronal signals compared with controls, according to a study published in the July Journal of Neurophysiology.

Molecular mechanisms: MeCP2 loss ups signal strength
Molecular mechanisms: Neuroligin-4 induces synapses in a dish
Neuroligin-4, a protein associated with autism, is located at synapses — the junctions between neurons — that inhibit signals in the brain, according to a study published in February in the Proceedings of the National Academy of Sciences. The protein can also single-handedly induce neurons derived from human stem cells to form synapses, according to another study in the same issue.

Molecular mechanisms: Neuroligin-4 induces synapses in a dish
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