Female protective effect
Recent articles
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
Autism is more heritable in boys than in girls
If boys have greater inherited liability for autism, the female protective effect may not fully explain the sex difference in prevalence.

Autism is more heritable in boys than in girls
If boys have greater inherited liability for autism, the female protective effect may not fully explain the sex difference in prevalence.
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.

Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
Genetic background sways effects of autism-linked mutation
Experiments offer clues to why certain mutations are associated with autism in some people and not others.

Genetic background sways effects of autism-linked mutation
Experiments offer clues to why certain mutations are associated with autism in some people and not others.
X-chromosome variants help explain autism’s sex bias
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.

X-chromosome variants help explain autism’s sex bias
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
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New questions around motor neurons and plasticity
A researcher’s theory hangs muscle degeneration on a broken neural circuit.

New questions around motor neurons and plasticity
A researcher’s theory hangs muscle degeneration on a broken neural circuit.
Boosting SCN2A expression reduces seizures in mice
A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.

Boosting SCN2A expression reduces seizures in mice
A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.
Nikolay Kukushkin discusses his book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind’
He explains how meaning arises in the interactions found throughout nature and evolution, from molecules to minds.
Nikolay Kukushkin discusses his book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind’
He explains how meaning arises in the interactions found throughout nature and evolution, from molecules to minds.