Gene
Recent articles
Autism-linked variants rewire protein networks
The myriad proteins tied to autism cluster in previously unrecognized ways that can be disrupted by specific variants in the proteins.
Autism-linked variants rewire protein networks
The myriad proteins tied to autism cluster in previously unrecognized ways that can be disrupted by specific variants in the proteins.
Nuclear location helps control gene activity during brain development
A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.
Nuclear location helps control gene activity during brain development
A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.
Virus-like particles deliver gene-editing tools into Duchenne mouse model
The approach uses a protein found in fruit flies to ferry the gene editor Cas9 into muscle cells.
Virus-like particles deliver gene-editing tools into Duchenne mouse model
The approach uses a protein found in fruit flies to ferry the gene editor Cas9 into muscle cells.
Textbook model of hippocampus’s role in memory may need updating
The CA3 region, long thought to have just one circuit, has two, sporting different wiring and functions, a new preprint suggests.
Textbook model of hippocampus’s role in memory may need updating
The CA3 region, long thought to have just one circuit, has two, sporting different wiring and functions, a new preprint suggests.
NeuroDev study maps previously unseen genetic variation in Africa
The project is helping to fill critical gaps in the genetic underpinnings of autism and other neurodevelopmental conditions.
NeuroDev study maps previously unseen genetic variation in Africa
The project is helping to fill critical gaps in the genetic underpinnings of autism and other neurodevelopmental conditions.
Cousin comparison parses genetic effects in autism
The approach helps reveal whether maternal genes contribute directly to autism in children or have indirect effects on the prenatal environment.
Cousin comparison parses genetic effects in autism
The approach helps reveal whether maternal genes contribute directly to autism in children or have indirect effects on the prenatal environment.
Advances in genetic medicine took center stage at INSAR
The president of the Autism Science Foundation and parent of a child with profound autism reflects on how advances in the treatment of rare gene variants bring hope to many families.
Advances in genetic medicine took center stage at INSAR
The president of the Autism Science Foundation and parent of a child with profound autism reflects on how advances in the treatment of rare gene variants bring hope to many families.
Gene activity in human cortex shows striking sex differences
The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.
Gene activity in human cortex shows striking sex differences
The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Exon-skipping approach boosts levels of key Rett syndrome protein
Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.
Exon-skipping approach boosts levels of key Rett syndrome protein
Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.
Explore more from The Transmitter
Fly taste connectome traces paths from sensation to action
The map—the first of its kind for an animal more complex than Caenorhabditis elegans—gives neuroscientists a trove of testable hypotheses about how neuronal circuits guide feeding behaviors.
Fly taste connectome traces paths from sensation to action
The map—the first of its kind for an animal more complex than Caenorhabditis elegans—gives neuroscientists a trove of testable hypotheses about how neuronal circuits guide feeding behaviors.
Remembering Gerry Fischbach, ‘orchestra conductor’ who brought scientists together
Fischbach, who died 25 October, elucidated the dynamic changes in neuromuscular junctions. Beyond the lab, he shaped careers, academic departments and scientific societies.
Remembering Gerry Fischbach, ‘orchestra conductor’ who brought scientists together
Fischbach, who died 25 October, elucidated the dynamic changes in neuromuscular junctions. Beyond the lab, he shaped careers, academic departments and scientific societies.
WILD platform levels up ability to record brain activity, behavior in nature
The customizable rig combines multimodal recording, onboard processing and neuronal manipulation to power more complex experiments.
WILD platform levels up ability to record brain activity, behavior in nature
The customizable rig combines multimodal recording, onboard processing and neuronal manipulation to power more complex experiments.