Gene

Recent articles

Two infants.

Cousin comparison parses genetic effects in autism

The approach helps reveal whether maternal genes contribute directly to autism in children or have indirect effects on the prenatal environment.

By Charles Q. Choi
18 June 2026 | 4 min read
DNA helix.

Advances in genetic medicine took center stage at INSAR

The president of the Autism Science Foundation and parent of a child with profound autism reflects on how advances in the treatment of rare gene variants bring hope to many families.

By Alison Singer
5 May 2026 | 4 min read
Research image of patterns of expression of autosomal genes.

Gene activity in human cortex shows striking sex differences

The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.

By Lauren Schenkman
5 May 2026 | 5 min read
Research image of zebrafish brain activity.

Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish

Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.

By Charles Q. Choi
16 April 2026 | 4 min read
DNA strand.

Exon-skipping approach boosts levels of key Rett syndrome protein

Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.

By Giorgia Guglielmi
20 March 2026 | 5 min read
Research image showing gene association.

Organoid study reveals shared brain pathways across autism-linked variants

The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.

By Giorgia Guglielmi
19 February 2026 | 4 min read
Crowd seen from above.

Common and rare variants shape distinct genetic architecture of autism in African Americans

Certain gene variants may have greater weight in determining autism likelihood for some populations, a new study shows.

By Laura Dattaro
15 January 2026 | 5 min read
A woman plays with a child on the floor.

Four autism subtypes map onto distinct genes, traits

An analysis of more than 5,000 autistic children and their siblings underscores the idea that autism can be understood as multiple conditions with distinct trajectories.

By Giorgia Guglielmi
17 July 2025 | 5 min read
Research image of frog cells.

Many autism-linked proteins influence hair-like cilia on human brain cells

The finding may help explain autism’s association with multiple co-occurring conditions that involve cilia defects.

By Charles Q. Choi
9 January 2025 | 4 min read
Human X and Y chromosomes.

Extra Y chromosomes are linked to autism

Data from people with more or fewer than two sex chromosomes could help answer questions around genetic protection and vulnerability.

By Grace Huckins
5 December 2024 | 5 min read

Explore more from The Transmitter

Photo collage featuring Tempest McDonald.

When autistic kids grow up, Chapter 3: Would there be data?

Tempest McDonald takes a postdoctoral position at Vanderbilt University. Researching her paper accusing the National Institutes of Health of discrimination threatens everything she has built.

By Brady Huggett
18 June 2026 | 27 min listen
A white brain model is surrounded by bright, detached sensory organs mounted on colorful wires.

Single-neuron recordings zoom into ‘blurry map’ of human motor cortex

The motor cortex is organized into an "intermixed jumble of tiles" to generate meaningful movement.

By Claudia López Lloreda
17 June 2026 | 5 min read
Computer code.

Exclusive: Neuroscience journal editor resigns over automation concerns

The editor resigned after the publisher’s artificial-intelligence system overrode his selection of referees for a manuscript. His move prompted an internal review of the system.

By Dalmeet Singh Chawla
17 June 2026 | 5 min read