Sex differences

Recent articles

Research image of patterns of expression of autosomal genes.

Gene activity in human cortex shows striking sex differences

The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.

By Lauren Schenkman
5 May 2026 | 5 min read

Large-scale neuroimaging datasets often lack information specific to women’s health, constraining AI’s analysis potential

Addressing this gap will require collecting widespread data on pregnancy, menopause and other life events women experience—and could bring us closer to the “holy grail” of linking brain and behavior.

By Amy Kuceyeski
16 March 2026 | 0 min watch
Research image of astrocytes in a mouse brain.

Astrocytes orchestrate oxytocin’s social effects in mice

The cells amplify oxytocin—and may be responsible for sex differences in social behavior, two preprints find.

By Holly Barker
4 March 2026 | 5 min read
Research image of male mouse placentas.

Post-infection immune conflict alters fetal development in some male mice

The immune conflict between dam and fetus could help explain sex differences in neurodevelopmental conditions.

By Viviane Callier
26 February 2026 | 5 min read
A boy and girl run in a field.

Sex bias in autism drops as age at diagnosis rises

The disparity begins to level out after age 10, raising questions about why so many autistic girls go undiagnosed earlier in childhood.

By Helena Kudiabor
13 February 2026 | 4 min read
A group of researchers reading while institutions crumble in the background, and giant mice appear on the horizon.

The Transmitter’s favorite essays of 2025

Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.

By The Transmitter
24 December 2025 | 2 min read
Developing human fetus.

Gene-activity map of developing brain reveals new clues about autism’s sex bias

Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.

By Giorgia Guglielmi
16 October 2025 | 5 min read
A drosophila connectome.

One year of FlyWire: How the resource is redefining Drosophila research

We asked nine neuroscientists how they are using FlyWire data in their labs, how the connectome has transformed the field and what new tools they would like to see in the future.

By Francisco J. Rivera Rosario
7 October 2025 | 17 min read
Illustration of a brain surrounded by a stylized silhouette of a human head with psychedelic colors and textures.

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

By Devin Effinger, Melissa Herman
1 October 2025 | 6 min read
Research image of microglia in organoids.

Microglia nurture young interneurons

The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”

By Lauren Schenkman
28 August 2025 | 3 min read

Explore more from The Transmitter

Illustration of needle sewing through multicolor strips.

How to use artificial intelligence to strengthen scientific processes and scholarly output

As AI-driven systems are integrated into all aspects of science, we need to make sure that they read and write to a shared data and knowledge space.

By Satrajit Ghosh
6 July 2026 | 5 min read
Research image of mitochondrial activity in the mouse amygdala and hippocampus.

The fast-expanding repertoire of mitochondria in the brain

More than cellular powerhouses, these organelles also seem to help synapses communicate, support memory formation and even shape behavior.

By Giorgia Guglielmi
3 July 2026 | 7 min read
Two fingers turning a small dial.

When autistic kids grow up, Chapter 5: The war dial

“You have to reshape the whole system.” Tempest McDonald earns a measure of peace.

By Brady Huggett
2 July 2026 | 42 min listen