Hippocampus

Recent articles

Photograph of a chickadee.

Gazing at a location from afar activates place cells in chickadees

The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.

By Marta Hill
13 June 2025 | 6 min listen
Illustration of synapse-like threads connecting in various ways.

Learning in living mice defies classic synaptic plasticity rule

Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

By Sydney Wyatt
28 May 2025 | 6 min listen
Image of brain cell activity in rat brains.

Sleep doesn’t just consolidate memories; it actively shapes them

The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.

By Giorgia Guglielmi
6 May 2025 | 6 min listen
Cognitive neuroscientist Nick Turk-Browne helps an infant into an fMRI machine.

What infant fMRI is revealing about the developing mind

Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.

By Calli McMurray
20 March 2025 | 12 min read
A mouse sits on a gloved hand.

Molecular changes after MECP2 loss may drive Rett syndrome traits

Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.

By Chloe Williams
20 March 2025 | 5 min read
Patient being administered an EEG test.

Single-neuron recordings are helping to unravel complexities of human cognition

As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”

By Claudia López Lloreda
14 March 2025 | 10 min listen

Alison Preston explains how our brains form mental frameworks for interpreting the world

Preston discusses her research examining differences in how children, teenagers and adults integrate new information into their memories.

By Paul Middlebrooks
12 March 2025 | 90 min listen
Dendritic spine images.

Targeting NMDA receptor subunit reverses fragile X traits in mice

The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.

By Angie Voyles Askham
6 March 2025 | 5 min read
Two bats in flight in black space.

Coding bonus: Bats’ hippocampal cells log spatial, social cues

The neurons represent not only an animal’s place in space, but also the distinguishing features of its fellow bats, including their sex and social status.

By Claudia López Lloreda
30 January 2025 | 5 min read
Eleanor Maguire.

Remembering Eleanor Maguire, ‘trailblazer’ of human memory

Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.

By Calli McMurray
10 January 2025 | 8 min read

Explore more from The Transmitter

Research image of organoids from autistic people.

Altered visual processing in a mouse model of fragile X syndrome; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 16 June.

By Jill Adams
17 June 2025 | 2 min read
Illustration of a fly in various poses.

This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day

This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

By Bradley Dickerson
17 June 2025 | 5 min listen
Hundred dollar bill digitally cut into small pieces.

NIH cuts quash $323 million for neuroscience research and training

“I am frightened for the state of the future of our field if this isn't reversed rapidly,” says Joshua Gordon, professor of psychiatry at Columbia University and former director of the National Institute of Mental Health.

By Claudia López Lloreda
16 June 2025 | 8 min read