Hippocampus
Recent articles
Machine learning spots neural progenitors in adult human brains
But the finding has not settled the long-standing debate over the existence and extent of neurogenesis during adulthood, says Yale University neuroscientist Juan Arellano.

Machine learning spots neural progenitors in adult human brains
But the finding has not settled the long-standing debate over the existence and extent of neurogenesis during adulthood, says Yale University neuroscientist Juan Arellano.
Spatial learning circuitry fluctuates in step with estrous cycle in mice
Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.

Spatial learning circuitry fluctuates in step with estrous cycle in mice
Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.
Expanded view of hippocampal function comes into focus
After decades of debate, the region’s role is being rewritten. Rather than using sensory input to simply log key points in time and space, the hippocampus may serve to contextualize our experiences and memories—and ultimately make predictions about the future.
Expanded view of hippocampal function comes into focus
After decades of debate, the region’s role is being rewritten. Rather than using sensory input to simply log key points in time and space, the hippocampus may serve to contextualize our experiences and memories—and ultimately make predictions about the future.
Gazing at a location from afar activates place cells in chickadees
The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.

Gazing at a location from afar activates place cells in chickadees
The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Sleep doesn’t just consolidate memories; it actively shapes them
The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.

Sleep doesn’t just consolidate memories; it actively shapes them
The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.
What infant fMRI is revealing about the developing mind
Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.

What infant fMRI is revealing about the developing mind
Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.
Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.

Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.
Single-neuron recordings are helping to unravel complexities of human cognition
As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”

Single-neuron recordings are helping to unravel complexities of human cognition
As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”
Alison Preston explains how our brains form mental frameworks for interpreting the world
Preston discusses her research examining differences in how children, teenagers and adults integrate new information into their memories.
Alison Preston explains how our brains form mental frameworks for interpreting the world
Preston discusses her research examining differences in how children, teenagers and adults integrate new information into their memories.
Explore more from The Transmitter
Authors retract Science paper on controversial fMRI method
Several known but usually negligible MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted earlier this month.

Authors retract Science paper on controversial fMRI method
Several known but usually negligible MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted earlier this month.
In memoriam: Stephanie “Steve” Shirley, autism philanthropist
Fueled by business success and her son, she played an outsized role in British autism research.

In memoriam: Stephanie “Steve” Shirley, autism philanthropist
Fueled by business success and her son, she played an outsized role in British autism research.
Ann Kennedy explains the theoretical neuroscience of survival behaviors
The Scripps neuroscientist calls for a broader theoretical neuroscience approach in her area of research, which focuses on how the subcortex bridges life and cognition.
Ann Kennedy explains the theoretical neuroscience of survival behaviors
The Scripps neuroscientist calls for a broader theoretical neuroscience approach in her area of research, which focuses on how the subcortex bridges life and cognition.