Learning
Recent articles
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Sleep doesn’t just consolidate memories; it actively shapes them
The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.

Sleep doesn’t just consolidate memories; it actively shapes them
The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.
What infant fMRI is revealing about the developing mind
Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.

What infant fMRI is revealing about the developing mind
Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.
Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.

Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.
Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.

Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.
The Transmitter’s favorite essays and columns of 2024
From sex differences in Alzheimer’s disease to enduring citation bias, experts weighed in on important scientific and practical issues in neuroscience.

The Transmitter’s favorite essays and columns of 2024
From sex differences in Alzheimer’s disease to enduring citation bias, experts weighed in on important scientific and practical issues in neuroscience.
The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.

The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.
Say what? The Transmitter’s top quotes of 2024
“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.

Say what? The Transmitter’s top quotes of 2024
“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.
Vijay Namboodiri and Ali Mohebi on the evolving story of dopamine’s role in cognitive function
Researchers discuss the classic stories of dopamine’s role in learning, ongoing work linking it to a wide variety of cognitive functions, and recent research suggesting that dopamine may help us "look back" to discover the causes of events in the world.
Vijay Namboodiri and Ali Mohebi on the evolving story of dopamine’s role in cognitive function
Researchers discuss the classic stories of dopamine’s role in learning, ongoing work linking it to a wide variety of cognitive functions, and recent research suggesting that dopamine may help us "look back" to discover the causes of events in the world.
Reconstructing dopamine’s link to reward
The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.

Reconstructing dopamine’s link to reward
The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.
Explore more from The Transmitter
On the importance of reading (just not too much)
The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.

On the importance of reading (just not too much)
The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.
How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.
NIH autism database announcement raises concerns among researchers
The U.S. National Institutes of Health announced a plan to pour $50 million into data science projects intended to investigate the condition’s causes, but the initiative’s short timeline and other atypicalities have prompted questions.

NIH autism database announcement raises concerns among researchers
The U.S. National Institutes of Health announced a plan to pour $50 million into data science projects intended to investigate the condition’s causes, but the initiative’s short timeline and other atypicalities have prompted questions.