Psychedelics

Recent articles

A mouse stands on a gloved hand.

Psychedelics research in rodents has a behavior problem

Simple behavioral assays—originally validated as drug-screening tools—fall short in studies that aim to unpack the psychedelic mechanism of action, so some behavioral neuroscientists are developing more nuanced tasks.

By Calli McMurray
19 December 2025 | 8 min read

Psilocybin rewires specific mouse cortical networks in lasting ways

Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops.

By Siddhant Pusdekar
5 December 2025 | 0 min watch
A man with glasses reads from a paper with a graph-like pattern of peaks and valleys on it.

The buzziest neuroscience papers of 2023, 2024

The field took note of work on brain-computer interfaces for speech, the mechanism of psychedelics, a broader definition of hippocampal representations, and more.

By Calli McMurray, Francisco J. Rivera Rosario
15 November 2025 | 18 min read
Research image of altered neurovascular coupling after exposure to psychedelics.

Psychedelics muddy fMRI results: Q&A with Adam Bauer and Jonah Padawer-Curry

The drugs disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help, the researchers say.

By Calli McMurray
29 October 2025 | 7 min read
Illustration of a brain surrounded by a stylized silhouette of a human head with psychedelic colors and textures.

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

By Devin Effinger, Melissa Herman
1 October 2025 | 6 min read
Crumpled pieces of paper form an X.

Psychedelics meta-analysis retracted after authors request ‘significant changes’

While working on a similar analysis last year, an independent researcher spotted inconsistencies in the now-retracted paper.

By Marta Hill
11 June 2025 | 2 min read

Explore more from The Transmitter

Research images of the mouse visual cortex.

Astrocytes stabilize circuits in adult mouse brain

The glial cells secrete a protein that suppresses plasticity post-development.

By Holly Barker
6 January 2026 | 5 min read
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Profiles of neurodevelopmental conditions; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 5 January.

By Jill Adams
6 January 2026 | 1 min read
Brain-shaped go-karts race.

The 1,000 neuron challenge

A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.

By Tom Stafford
5 January 2026 | 7 min read

privacy consent banner

Privacy Preference

We use cookies to provide you with the best online experience. By clicking “Accept All,” you help us understand how our site is used and enhance its performance. You can change your choice at any time. To learn more, please visit our Privacy Policy.