Schizophrenia

Recent articles

Illustration of a line graph emanating from a beaker.

Null and Noteworthy, relaunched: Probing a schizophrenia biomarker

This edition of Null and Noteworthy—the first for The Transmitter—highlights new findings about the auditory steady-state response in people with schizophrenia that, all within one study, somehow packed in a null result and a failed replication.

By Laura Dattaro
28 February 2025 | 5 min read
Illustration of two silhouettes overlaid by opaque square panels.

Why hasn’t genetics taught us more about schizophrenia?

Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.

By Joshua R. Sanes
18 February 2025 | 8 min read

Assembloids illuminate circuit-level changes linked to autism, neurodevelopment

These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.

By Sarah DeWeerdt
19 December 2024 | 0 min watch
Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read
A younger looking set of hands holds an older looking set of hands.

New catalog charts familial ties from autism to 90 other conditions

The research tool reveals associations stretching across three generations.

By Charles Q. Choi
17 October 2024 | 4 min read
Stock photograph of a women and her young child at a clinician’s office.

A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman

A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.

By Lauren Schenkman
15 August 2024 | 7 min read
Research image of a chimeroid.

Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics

These fusions created from multiple donors’ organoids may help scale up comparative brain research.

By Charles Q. Choi
5 July 2024 | 4 min read
Research image of brain activity

Connectivity takes U-turn in people with rare autism-linked mutations

Patterns of brain connectivity shift during puberty in people with deletion of the 22q11.2 chromosomal region.

By Holly Barker
30 May 2024 | 4 min read
A research image showing astrocytes and neurons

‘SNAP’ dance of astrocytes and neurons falls out of step with age, disease

The findings add to growing evidence that astrocytes are star players in cognition.

By Laura Dattaro
6 March 2024 | 6 min read
A grid of four brain scans showing excess cerebrospinal fluid.

Is excess brain fluid an early marker of autism?

Brain scans of hundreds of infants suggest that up to 80 percent of those with autism have unusual amounts of cerebrospinal fluid. Researchers are studying how this might contribute to the condition.

By Giorgia Guglielmi
17 August 2023 | 10 min read

Explore more from The Transmitter

Diego Bohorquez portrait on blue background.

The big idea with Diego Bohórquez

His theories around the neuropod have challenged the boundaries of classic ideas regarding gut-brain communication.

By Sydney Wyatt
20 June 2025 | 14 min listen
Two paper arrows intersect to form a double helix.

Genetic background steers PTEN syndrome traits

People with the syndrome, caused by variants in the gene PTEN, often have autism or cancer, or both, but it depends on the genetic diversity encoded in the components of distinct cell signaling pathways, according to a new study.

By Holly Barker
19 June 2025 | 5 min listen
Photograph of a moth.

Star-responsive neurons steer moths’ long-distance migration

Cells in the bogong moth brain respond to astral landmarks to orient the insects in the direction they need to go.

By Angie Voyles Askham
18 June 2025 | 5 min listen