Social reward

Position heatmaps of mice performing a behavioral assay.

New test taps nose pokes as a proxy for social motivation in mice

Over one hour, a particularly motivated mouse poked its nose 350 times into a hole in the test chamber in the hopes of meeting a playmate.

By Holly Barker
10 August 2023 | 5 min read
A photograph of a mouse against a swirly, multi-colored backdrop

Psychedelics give mice second chance to learn social rewards

The drugs may reopen a critical window during development in which the brain can more easily adjust its connections.

By Holly Barker
23 June 2023 | 4 min read
Illustration shows two octopi interacting on a yellow background.
Spectrum Microphone

Getting eight arms around autism

Octopuses can solve some of the same problems as people but do so in unusual ways.

By Sarah DeWeerdt
8 September 2021 | 4 min listen

Drugs boost serotonin, socialization in multiple autism mouse models

The finding that MDMA and an experimental serotonin agonist increase sociability across six different model mice suggests that disparate autism-linked mutations converge on the same underlying pathways.

By Peter Hess
6 August 2021 | 4 min read
Boy in front of colorful constellation or universe, studying the realms of outer space.

The benefits of special interests in autism

Researchers are studying how the intense passions of autistic people shape the brain, improve well-being and enhance learning.

By Emily Laber-Warren
12 May 2021 | 18 min read
Brain scan showing communication from amygdala to hypothalamus about social reward.

Brain circuit makes social interactions rewarding, may be altered in autism

Blocking connections between the amygdala and hypothalamus prevents mice from finding social interactions as rewarding as they would otherwise.

By Angie Voyles Askham
30 April 2021 | 4 min read
dopamine neurons in mice show up green in an area of the brain associated with social reward.

Dopamine neurons may dampen social behavior in mouse model of autism

Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.

By Peter Hess
12 January 2021 | 4 min read
Oxytocin neurons stained pink and green.

Autism-linked gene exerts varied effects on oxytocin circuits in mice

Two types of neurons process social information, a new mouse study suggests, but only one is disrupted in mice missing the autism-linked gene FMR1.

By Peter Hess
18 December 2020 | 4 min read
Toddler vocalizing with parent.
Spectrum Microphone

Social motivation predicts language skills in autistic children

The more children with autism tune in to and communicate with others as toddlers, the stronger their conversation skills are later in childhood.

By Angie Voyles Askham
8 October 2020 | 4 min read
Illustration shows scientist is observing social behavior in a large group of children

In search of ‘social’ subtypes of autism

Grouping autistic people based on their social abilities may reveal subtypes of the condition.

By Thomas Frazier, Mirko Uljarević
21 July 2020 | 5 min read

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Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
Illustration of researchers talking to laypeople amidst strands of DNA.

Building an autism research registry: Q&A with Tony Charman

A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.

By Cathleen O’Grady
25 July 2024 | 8 min read

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read