Social reward
New test taps nose pokes as a proxy for social motivation in mice
Over one hour, a particularly motivated mouse poked its nose 350 times into a hole in the test chamber in the hopes of meeting a playmate.
![Position heatmaps of mice performing a behavioral assay.](https://www.thetransmitter.org/wp-content/uploads/2023/08/1200-social-motivation-assay-autism.png)
New test taps nose pokes as a proxy for social motivation in mice
Over one hour, a particularly motivated mouse poked its nose 350 times into a hole in the test chamber in the hopes of meeting a playmate.
Psychedelics give mice second chance to learn social rewards
The drugs may reopen a critical window during development in which the brain can more easily adjust its connections.
![A photograph of a mouse against a swirly, multi-colored backdrop](https://www.thetransmitter.org/wp-content/uploads/2023/06/1200-psychedelics-social-reward-learning-autism.png)
Psychedelics give mice second chance to learn social rewards
The drugs may reopen a critical window during development in which the brain can more easily adjust its connections.
Getting eight arms around autism
Octopuses can solve some of the same problems as people but do so in unusual ways.
![Illustration shows two octopi interacting on a yellow background.](https://www.thetransmitter.org/wp-content/uploads/1970/01/Octopus844.jpg)
Getting eight arms around autism
Octopuses can solve some of the same problems as people but do so in unusual ways.
Drugs boost serotonin, socialization in multiple autism mouse models
The finding that MDMA and an experimental serotonin agonist increase sociability across six different model mice suggests that disparate autism-linked mutations converge on the same underlying pathways.
![](https://www.thetransmitter.org/wp-content/uploads/2021/08/20210806-Serotonin844.jpg)
Drugs boost serotonin, socialization in multiple autism mouse models
The finding that MDMA and an experimental serotonin agonist increase sociability across six different model mice suggests that disparate autism-linked mutations converge on the same underlying pathways.
The benefits of special interests in autism
Researchers are studying how the intense passions of autistic people shape the brain, improve well-being and enhance learning.
![Boy in front of colorful constellation or universe, studying the realms of outer space.](https://www.thetransmitter.org/wp-content/uploads/2021/05/SpecialInterestsLead844.jpg)
The benefits of special interests in autism
Researchers are studying how the intense passions of autistic people shape the brain, improve well-being and enhance learning.
Brain circuit makes social interactions rewarding, may be altered in autism
Blocking connections between the amygdala and hypothalamus prevents mice from finding social interactions as rewarding as they would otherwise.
![Brain scan showing communication from amygdala to hypothalamus about social reward.](https://www.thetransmitter.org/wp-content/uploads/2021/04/20210430-AmydalaHypothalamus-844.jpg)
Brain circuit makes social interactions rewarding, may be altered in autism
Blocking connections between the amygdala and hypothalamus prevents mice from finding social interactions as rewarding as they would otherwise.
Dopamine neurons may dampen social behavior in mouse model of autism
Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.
![dopamine neurons in mice show up green in an area of the brain associated with social reward.](https://www.thetransmitter.org/wp-content/uploads/2021/01/Dopamine-844.jpg)
Dopamine neurons may dampen social behavior in mouse model of autism
Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.
Autism-linked gene exerts varied effects on oxytocin circuits in mice
Two types of neurons process social information, a new mouse study suggests, but only one is disrupted in mice missing the autism-linked gene FMR1.
![Oxytocin neurons stained pink and green.](https://www.thetransmitter.org/wp-content/uploads/2020/12/20201214-ParallelSocial-844.jpg)
Autism-linked gene exerts varied effects on oxytocin circuits in mice
Two types of neurons process social information, a new mouse study suggests, but only one is disrupted in mice missing the autism-linked gene FMR1.
Social motivation predicts language skills in autistic children
The more children with autism tune in to and communicate with others as toddlers, the stronger their conversation skills are later in childhood.
![Toddler vocalizing with parent.](https://www.thetransmitter.org/wp-content/uploads/2020/10/20201008-Toddler844.jpg)
Social motivation predicts language skills in autistic children
The more children with autism tune in to and communicate with others as toddlers, the stronger their conversation skills are later in childhood.
In search of ‘social’ subtypes of autism
Grouping autistic people based on their social abilities may reveal subtypes of the condition.
![Illustration shows scientist is observing social behavior in a large group of children](https://www.thetransmitter.org/wp-content/uploads/2021/01/20200721-Frazier844.jpg)
In search of ‘social’ subtypes of autism
Grouping autistic people based on their social abilities may reveal subtypes of the condition.
Explore more from The Transmitter
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
![Research image of neurons in the fly’s ventral nerve cord.](https://www.thetransmitter.org/wp-content/uploads/2024/07/lede-motormodules-1200-1024x692.webp)
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
Building an autism research registry: Q&A with Tony Charman
A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.
![Illustration of researchers talking to laypeople amidst strands of DNA.](https://www.thetransmitter.org/wp-content/uploads/2024/07/1200_Charman-1024x687.webp)
Building an autism research registry: Q&A with Tony Charman
A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
![](https://www.thetransmitter.org/wp-content/uploads/2024/07/paincircuit-1200-1024x692.webp)
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.