Anxiety

Recent articles

Illustration of a brain surrounded by a stylized silhouette of a human head with psychedelic colors and textures.

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

By Devin Effinger, Melissa Herman
1 October 2025 | 7 min listen
Hands arrange various shapes over a color background.

Emotion research has a communication conundrum

In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.

By Nicole Rust
5 September 2025 | 37 min listen
Research image of neurons in the interpeduncular nucleus.

‘Understudied secret’ in brain dampens nicotine drive in mice

The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

By Lauren Schenkman
4 June 2025 | 5 min listen
Tiger in a brain scanner.

Lions and tigers and bears: Long-lived zoo animals offer a promising venue to study mental health and neurodegenerative disorders

These animals’ lifestyles often mirror those of people, making them a more relevant milieu than lab mice for determining how environmental factors influence mental health and cognitive decline. Studying them could improve animal welfare in the process.

By Christine J. Charvet
17 March 2025 | 5 min read
Illustration of a body, brain visible through a transparent head, looking at orange circles over its hands.

Rethinking mental health: The body’s impact on the brain

Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.

By Georgia E. Hodes
11 February 2025 | 6 min read
Two rhesus macaque monkeys.

Vasopressin boosts sociability in solitary monkeys

Inhaling the hormone did not increase aggression in unsociable rhesus macaques and appears to help the animals remember faces and reciprocate friendly behaviors.

By Charles Q. Choi
25 November 2024 | 5 min read
Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read
Illustration of a mouse with cheese on its left and a drop of water on its right.

Should I stay (and eat) or should I go? How the brain balances hunger with competing drives

Understanding the interplay among rival signals, such as pain, thirst and fear, could provide insights into anxiety and other neuropsychiatric conditions.

By Giorgia Guglielmi
11 October 2024 | 8 min read
Image of the dorsal raphe area of the brain.

Neurotransmitter switch-up helps fan extreme stress into full-blown fear

The flip occurs when certain neurons in the dorsal raphe start to express the chemical GABA instead of glutamate, a new study shows.

By Claudia López Lloreda
9 April 2024 | 5 min read
Research image of microglia in rats.

Temperament is innate but hackable, animal studies suggest

Emotional reactivity and vulnerability to stress are largely inherited in rodents — but can be modified in early life by targeting inflammation-related cells or even just adjusting an animal’s environment.

By Holly Barker
23 January 2024 | 8 min read

Explore more from The Transmitter

Nonhuman primate research to lose federal funding at major European facility

The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.

By Lauren Schenkman
30 October 2025 | 4 min read

Image integrity issues create new headache for subarachnoid hemorrhage research

First-time sleuths found potentially problematic images in hundreds of papers about early brain injury after subarachnoid hemorrhage.

By Lauren Schneider
30 October 2025 | 5 min read
Research image of mouse brain slices stained in red and blue.

Ramping up cortical activity in early life sparks autism-like behaviors in mice

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

By Sarah DeWeerdt
30 October 2025 | 6 min read

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