Sex differences

Recent articles

A group of researchers reading while institutions crumble in the background, and giant mice appear on the horizon.

The Transmitter’s favorite essays of 2025

Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.

By The Transmitter
24 December 2025 | 2 min read
Developing human fetus.

Gene-activity map of developing brain reveals new clues about autism’s sex bias

Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.

By Giorgia Guglielmi
16 October 2025 | 5 min read
A drosophila connectome.

One year of FlyWire: How the resource is redefining Drosophila research

We asked nine neuroscientists how they are using FlyWire data in their labs, how the connectome has transformed the field and what new tools they would like to see in the future.

By Francisco J. Rivera Rosario
7 October 2025 | 17 min read
Illustration of a brain surrounded by a stylized silhouette of a human head with psychedelic colors and textures.

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

By Devin Effinger, Melissa Herman
1 October 2025 | 6 min read
Research image of microglia in organoids.

Microglia nurture young interneurons

The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”

By Lauren Schenkman
28 August 2025 | 3 min read
A brain made up of digital text.

ABCD Study omits gender-identity data from latest release

The removal counteracts the goals of the longitudinal study by “pretending that some aspects of adolescent brain development don’t exist,” says sex differences researcher Nicola Grissom.

By Calli McMurray
11 July 2025 | 4 min read
Illustration of overlapping, multi-colored human head silhouettes.

Perspectives from the field: Opinions in autism research

This collection of Spectrum articles from the past 12 months highlights expert perspectives on autism’s heritability and its link to biological sex, the value of transdiagnostic frameworks, and the field’s future, among other topics.

By Daisy Yuhas
10 July 2025 | 3 min read
Research image of excitatory neurons in the mouse hippocampus.

Spatial learning circuitry fluctuates in step with estrous cycle in mice

Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.

By Sydney Wyatt
25 June 2025 | 5 min read
Research image of the spinal meninges in mice.

Immune cells block pain in female mice only

Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.

By Angie Voyles Askham
22 May 2025 | 5 min read
Photograph of a cardinal with male-typical red feathers on one side and more drab, female-typical feathers on the other.

What birds can teach us about the ‘biological truth’ of sex

Part of our job as educators is to give students a deeper understanding of the true diversity of sex and gender in the natural world.

By Nicole M. Baran
22 April 2025 | 7 min read

Explore more from The Transmitter

Snoozing dragons stir up ancient evidence of sleep’s dual nature

Deep-sleep cycling between brain waves of higher and lower amplitude dates far back on the evolutionary tree, according to a new comparative study of mammals and reptiles.

By Lauren Schenkman
29 December 2025 | 0 min watch
Books.

The Transmitter’s most-read neuroscience book excerpts of 2025

Books by Nachum Ulanovsky, Nicole Rust, and Andrew Iwaniuk and Georg Striedter made the list of some of the year's most engaging neuroscience titles.

By The Transmitter
24 December 2025 | 2 min read
Nachum Ulanovsky sits against a black background with one bat in his hands and another with its wings spread above his head.

Neuroscience’s leaders, legacies and rising stars of 2025

Here are seven stories from the past year about some of the field’s most engaging figures.

By The Transmitter
24 December 2025 | 2 min read

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