Stem cells

Recent articles

Cell ‘antennae’ link autism, congenital heart disease

Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.

By Lauren Schenkman
24 July 2025 | 4 min listen
Research image of human cortical neurons xenotransplanted into a mouse brain for months.

In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain

Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.

By Pierre Vanderhaeghen
7 April 2025 | 9 min listen
Research image of an assembloid.

Organoids and assembloids offer a new window into human brain

These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.

By Sergiu P. Pasca
31 March 2025 | 7 min read
Research image of brain scans.

Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions

Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.

By Holly Barker
12 December 2024 | 5 min read
Black-and-white research image of brain organoids.

Brain organoid size matches intensity of social problems in autistic people

Overgrown organoids could point to mechanisms underlying profound autism.

By Holly Barker
18 July 2024 | 5 min read
Neural progenitor cells in a culture medium, color-enhanced scanning electron micrograph (SEM).

Autism subgroups converge on cell growth pathway

Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.

By Angie Voyles Askham
2 April 2024 | 5 min listen
An illustration of a gold circle and wavy blue plants.

Building a brain: How does it generate its exquisite diversity of cells?

High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.

By Tomasz Nowakowski, Karthik Shekhar
18 March 2024 | 6 min read
A scientist looks into a microscope

Raising the bar for stem cell research: Q&A with Jack Mosher

New quality benchmarks for basic research involving stem cells promise to improve rigor and reproducibility, says Mosher, who helped develop the standards.

By Lauren Schenkman
10 October 2023 | 7 min read

Autism’s ties to the cell skeleton

Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.

By Giorgia Guglielmi
22 June 2023 | 7 min read
Research image of neurons and astrocytes.

Astrocytes fuel erratic firing in fragile X neurons

A shift in astrocyte secretions may explain the atypical firing patterns of neurons derived from people with fragile X syndrome.

By Lauren Schenkman
10 May 2023 | 5 min read

Explore more from The Transmitter

Illustration of the outlines of a baby, a bee and a robot filled in with computer code-like characters.

Babies, bees and bots: On the hunt for markers of consciousness

To truly understand consciousness, we need new methods to measure it and detect it in other intelligent systems.

By Tim Bayne
30 July 2025 | 6 min read

Jennifer Prendki explains why AI needs to emulate life

Prendki describes how her work on large artificial-intelligence models shaped her view that current AI needs inspiration from living organisms.

By Paul Middlebrooks
30 July 2025 | 109 min listen
Research visualization of reverberating activity in a selection of higher-order brain areas.

Eye puffs prompt separable sensory, affective brain responses in mice, people

Post-puff brain state might not be an emotion, some researchers caution, but the protocol provides a cross-species approach to study emotions.

By Calli McMurray
29 July 2025 | 8 min listen