Drosophila
Recent articles
Exclusive: Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.

Exclusive: Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.
Cross-species connectome comparison shows uneven olfactory circuit evolution in flies
The findings start to reveal evolutionary changes that may have helped two species develop different olfactory preferences and adapt to their particular environments.

Cross-species connectome comparison shows uneven olfactory circuit evolution in flies
The findings start to reveal evolutionary changes that may have helped two species develop different olfactory preferences and adapt to their particular environments.
Systems and circuit neuroscience need an evolutionary perspective
To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.

Systems and circuit neuroscience need an evolutionary perspective
To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.
This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day
This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day
This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.
How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.
FlyBase funding squashed amid Harvard grant terminations
The team behind the Drosophila genetics database is now requesting donations from labs to keep the resource afloat.

FlyBase funding squashed amid Harvard grant terminations
The team behind the Drosophila genetics database is now requesting donations from labs to keep the resource afloat.
Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.

Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.
Why practical summer courses in neuroscience matter
Among other reasons, this tradition helps researchers rekindle the unfettered joy that initially brought them to the field.

Why practical summer courses in neuroscience matter
Among other reasons, this tradition helps researchers rekindle the unfettered joy that initially brought them to the field.
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
To develop better nervous-system visualizations, we need to think BIG
With a full mouse connectome on the horizon, neuroscience needs to overcome its legacy of minimalism and embrace the contemporary challenge of representing whole-nervous-system connectivity.

To develop better nervous-system visualizations, we need to think BIG
With a full mouse connectome on the horizon, neuroscience needs to overcome its legacy of minimalism and embrace the contemporary challenge of representing whole-nervous-system connectivity.
Explore more from The Transmitter
Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.

Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”

Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Xaq Pitkow shares his principles for studying cognition in our imperfect brains and bodies
Pitkow discusses how evolution's messy constraints shape optimal brain algorithms, from Bayesian inference to ecological affordances.
Xaq Pitkow shares his principles for studying cognition in our imperfect brains and bodies
Pitkow discusses how evolution's messy constraints shape optimal brain algorithms, from Bayesian inference to ecological affordances.