Gene regulation

Recent articles

Illustration of cells converting from fibroblasts to myoblasts.

This paper changed my life: Learning the molecular rules of cell identity

A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.

By Ardem Patapoutian
17 June 2026 | 6 min read

Ant olfactory neurons reveal new ‘transcriptional shield’ mechanism of gene regulation

A protective screen of spurious transcriptional activity enables each olfactory neuron to express exactly one out of hundreds of olfactory receptors.

By Viviane Callier
14 October 2025 | 0 min watch

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Cortical area remixes macaques’ knowledge blocks to solve new problems

When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.

By Lauren Schenkman
19 June 2026 | 0 min watch
Photo illustration of Kaela Singleton.

Getting grants feels good, but giving them is even better

As director of grants management at the Cure Alzheimer’s Fund, Kaela Singleton bets on bold science and shares in the joy of discovery.

By Katie Moisse
19 June 2026 | 8 min read
Photo collage featuring Tempest McDonald.

When autistic kids grow up, Chapter 3: Would there be data?

Tempest McDonald takes a postdoctoral position at Vanderbilt University. Researching her paper accusing the National Institutes of Health of discrimination threatens everything she has built.

By Brady Huggett
18 June 2026 | 27 min listen