Gene regulation

Recent articles

Illustration of cells converting from fibroblasts to myoblasts.

This paper changed my life: Learning the molecular rules of cell identity

A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.

By Ardem Patapoutian
17 June 2026 | 6 min read

Ant olfactory neurons reveal new ‘transcriptional shield’ mechanism of gene regulation

A protective screen of spurious transcriptional activity enables each olfactory neuron to express exactly one out of hundreds of olfactory receptors.

By Viviane Callier
14 October 2025 | 0 min watch

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Cortical organoids.

Five-year-old human brain organoids aged on schedule

The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.

By Claudia López Lloreda
19 August 2026 | 5 min read

Brainstem neurons add new element to ‘already complex’ anxiety circuitry

Precise optogenetic modulation of a medullary neuron population reveals their role in anxiety-like behaviors.

By Sarah Thau
19 August 2026 | 0 min watch