Immune system

Recent articles

Brain scans showing activity in areas associated with threat detection and peripersonal space.

Human brain may anticipate looming contagion

Seeing a visibly ill avatar in virtual reality activates a neuroimmune pathway in brain areas related to peripersonal space and prompts an immune response, a small new study suggests.

By Claudia López Lloreda
28 July 2025 | 6 min read
Research image of the spinal meninges in mice.

Immune cells block pain in female mice only

Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.

By Angie Voyles Askham
22 May 2025 | 6 min listen
Illustration of a body, brain visible through a transparent head, looking at orange circles over its hands.

Rethinking mental health: The body’s impact on the brain

Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.

By Georgia E. Hodes
11 February 2025 | 6 min read
Research image of mouse cells.

Immune cell interlopers breach—and repair—brain barrier in mice

The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.

By Claudia López Lloreda
20 November 2024 | 6 min listen
Research image of microglia in mice.

Microglial overreaction to atypical neurons may drive autism

In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.

By Holly Barker
21 March 2024 | 5 min read
A research image of a mouse brain

Immune-activation model mice escape infantile amnesia, retain early memories

Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.

By Giorgia Guglielmi
11 January 2024 | 5 min read
A multiplexed image of human decidua.

Atlas charts cells of human placenta, uterus across early pregnancy

A new resource gives an unparalleled look at how fetal placental cells attach to the uterine wall and remodel maternal blood vessels to access nutrients.

By Emily Hayes
27 July 2023 | 4 min read

‘wildDISCO’ cocktail yields whole-body maps of mouse neurons and more

A new technique used to create see-through rodents can help scientists analyze how the nervous system interacts with other body systems.

By Charles Q. Choi
20 July 2023 | 4 min read
Research image comparing microglia with serotonin receptors to those without.

Serotonin powers pruning of developing brain circuits in mice

Mice with microglia missing receptors for the neurotransmitter serotonin since birth have too many synapses and show social difficulties in adulthood.

By Katie Moisse
28 June 2023 | 5 min listen
Research image of the posterior insular cortex.

Maternal immune response dulls male rats’ social radar

Male rats prenatally exposed to a maternal immune response have atypical responses to other rats in distress, according to a new study.

By Angie Voyles Askham
27 March 2023 | 6 min listen

Explore more from The Transmitter

Chris Rozell explains how brain stimulation and AI are helping to treat mental disorders

Rozell and his colleagues, using deep brain stimulation and explainable artificial intelligence, have developed tools to help people with treatment-resistant depression.

By Paul Middlebrooks
13 August 2025 | 1 min read
Illustration of a musical staff with notes represented by neurons.

This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations

By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.

By Abigail Person
12 August 2025 | 6 min listen
Research image of mouse auditory brainstems.

Prosocial effects of oxytocin are state dependent; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 11 August.

By Jill Adams
12 August 2025 | 2 min read