Methods
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
![Research image of neurons in the fly’s ventral nerve cord.](https://www.thetransmitter.org/wp-content/uploads/2024/07/lede-motormodules-1200-1024x692.webp)
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
New ‘decoder’ tool translates functional neuroimaging terms across labs
The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.
![Research image of a variety of brain atlases.](https://www.thetransmitter.org/wp-content/uploads/2024/07/Fig2B-1200-1024x692.webp)
New ‘decoder’ tool translates functional neuroimaging terms across labs
The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.
To develop better nervous-system visualizations, we need to think BIG
With a full mouse connectome on the horizon, neuroscience needs to overcome its legacy of minimalism and embrace the contemporary challenge of representing whole-nervous-system connectivity.
![A dense reconstruction of layer 2/3 neurons of the mouse visual cortex containing 394 neurons and 3.2 million synapses.](https://www.thetransmitter.org/wp-content/uploads/2024/07/Figure1-Sloan-1200-1024x692.webp)
To develop better nervous-system visualizations, we need to think BIG
With a full mouse connectome on the horizon, neuroscience needs to overcome its legacy of minimalism and embrace the contemporary challenge of representing whole-nervous-system connectivity.
Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics
These fusions created from multiple donors’ organoids may help scale up comparative brain research.
![Research image of a chimeroid.](https://www.thetransmitter.org/wp-content/uploads/2024/07/Chimeroid-Lede-1200-1024x692.webp)
Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics
These fusions created from multiple donors’ organoids may help scale up comparative brain research.
How to teach this paper: ‘Behavioral time scale synaptic plasticity underlies CA1 place fields,’ by Bittner and Milstein et al. (2017)
Katie Bittner, Aaron Milstein and their colleagues found that cellular learning can happen over longer timescales than Hebb’s rule predicts. How long should we wait to teach students about this phenomenon?
![Illustration of a canyon landscape with an orange clock face in place of a sun.](https://www.thetransmitter.org/wp-content/uploads/2024/06/1200-how-to-teach-3-transmitter-neuroscience-1024x683.webp)
How to teach this paper: ‘Behavioral time scale synaptic plasticity underlies CA1 place fields,’ by Bittner and Milstein et al. (2017)
Katie Bittner, Aaron Milstein and their colleagues found that cellular learning can happen over longer timescales than Hebb’s rule predicts. How long should we wait to teach students about this phenomenon?
Widely used calcium imaging protocol can lead to spurious results, new paper cautions
The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.
Widely used calcium imaging protocol can lead to spurious results, new paper cautions
The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Brain connectivity and letting the data speak with Emily Finn
The Dartmouth College researcher talks about her quest to understand behavior and doing neuroscience “in the woods.”
![Illustrated portrait of Emily Finn.](https://www.thetransmitter.org/wp-content/uploads/2024/05/1200-emily-finn-synaptic-neuroscience-transmitter-1024x692.webp)
Brain connectivity and letting the data speak with Emily Finn
The Dartmouth College researcher talks about her quest to understand behavior and doing neuroscience “in the woods.”
How to use race and ethnicity data responsibly in neuroscience research
Follow these four tips to avoid using the information in problematic ways, including as a proxy for environmental variables.
![](https://www.thetransmitter.org/wp-content/uploads/2024/04/Race-Ethnicity-research-1200-1024x692.webp)
How to use race and ethnicity data responsibly in neuroscience research
Follow these four tips to avoid using the information in problematic ways, including as a proxy for environmental variables.
To improve big data, we need small-scale human imaging studies
By insisting that every brain-behavior association study include hundreds or even thousands of participants, we risk stifling innovation. Smaller studies are essential to test new scanning paradigms.
![Illustration of a hand reaching out to adjust a dial that sits in the middle of several images depicting brain activity and various behaviors.](https://www.thetransmitter.org/wp-content/uploads/2024/04/1200-transmitter-neuroscience-small-scale-imaging-studies-1024x683.webp)
To improve big data, we need small-scale human imaging studies
By insisting that every brain-behavior association study include hundreds or even thousands of participants, we risk stifling innovation. Smaller studies are essential to test new scanning paradigms.
Explore more from The Transmitter
Building an autism research registry: Q&A with Tony Charman
A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.
![Illustration of researchers talking to laypeople amidst strands of DNA.](https://www.thetransmitter.org/wp-content/uploads/2024/07/1200_Charman-1024x687.webp)
Building an autism research registry: Q&A with Tony Charman
A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
![](https://www.thetransmitter.org/wp-content/uploads/2024/07/paincircuit-1200-1024x692.webp)
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
CNTNAP2 variants; trait trajectories; sensory reactivity
Here is a roundup of autism-related news and research spotted around the web for the week of 22 July.
![Research image showing connectivity in brain regions in female mice with and without a UBE3A variant.](https://www.thetransmitter.org/wp-content/uploads/2024/07/autism-sexbias-1200-1024x692.webp)
CNTNAP2 variants; trait trajectories; sensory reactivity
Here is a roundup of autism-related news and research spotted around the web for the week of 22 July.