Neuropixels

Recent articles

Concentric circles.

What are the most transformative neuroscience tools and technologies developed in the past five years?

Artificial intelligence and deep-learning methods featured prominently in the survey responses, followed by genetic tools to control circuits, advanced neuroimaging, transcriptomics and various approaches to record brain activity and behavior.

By The Transmitter
15 November 2025 | 14 min read
Speech bubbles and images of a brain overlaid on a globe.

A community-designed experiment tests open questions in predictive processing

More than 50 scientists came together to identify the key missing data needed to rigorously test theoretical models.

By Jérôme Lecoq
12 November 2025 | 6 min read
Research image of red and blue light emitted from the Neuropixels Opto probe.

‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures

The tool provides a new way to characterize cells and study neuronal circuits.

By Claudia López Lloreda
29 April 2025 | 4 min read
Mock-up of the Neuropixels probe inserted into brain tissue.

Tracking single neurons in the human brain reveals new insight into language and other human-specific functions

Better technologies to stably monitor cell populations over long periods of time make it possible to study neural coding and dynamics in the human brain.

By Edward Chang, Jason Chung
28 April 2025 | 7 min read

Explore more from The Transmitter

Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Autism-linked genes alter sleep behavior, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 13 April.

By Jill Adams
14 April 2026 | 2 min read
Illustration of a monkey pushing a button.

This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli

A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think deeply about factors that influence how behavior is generated and maintained.

By Erin Calipari
14 April 2026 | 5 min read
Illustration of a sheet of paper with a topography map-like pattern on it.

Why neural foundation models work, and what they might—and might not—teach us about the brain

These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity. But will we be able to understand them?

By Juan Gallego
13 April 2026 | 8 min read