Optogenetics
Recent articles
Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.
Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.
Facial movements telegraph cognition in mice
If you give a mouse a decision, its thought process may show on its face.
Facial movements telegraph cognition in mice
If you give a mouse a decision, its thought process may show on its face.
New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures
The tool provides a new way to characterize cells and study neuronal circuits.
‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures
The tool provides a new way to characterize cells and study neuronal circuits.
Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.
Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.
Putting a bright idea to the test
A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.
Putting a bright idea to the test
A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.
Climbing to new heights: Q&A with Kaspar Podgorski
The optical physiologist tracks neural computations inside the lab and scales sheer rock faces outside—even after a life-changing fall.
Climbing to new heights: Q&A with Kaspar Podgorski
The optical physiologist tracks neural computations inside the lab and scales sheer rock faces outside—even after a life-changing fall.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Learning or performance? Why the distinction matters for memory science
New methods make it possible to probe the neural substrates of memory with unprecedented precision. Making the most of them demands careful experimental design.
Learning or performance? Why the distinction matters for memory science
New methods make it possible to probe the neural substrates of memory with unprecedented precision. Making the most of them demands careful experimental design.
Newly found hypothalamus circuits shape bullying behaviors in mice
Activity in the tiny brain region helps submissive rodents learn to avoid aggressors, and aggressive mice to curb their attacks, according to two recent studies.
Newly found hypothalamus circuits shape bullying behaviors in mice
Activity in the tiny brain region helps submissive rodents learn to avoid aggressors, and aggressive mice to curb their attacks, according to two recent studies.
Explore more from The Transmitter
Nonhuman primate research to lose federal funding at major European facility
The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.
Nonhuman primate research to lose federal funding at major European facility
The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.
Image integrity issues create new headache for subarachnoid hemorrhage research
First-time sleuths found potentially problematic images in hundreds of papers about early brain injury after subarachnoid hemorrhage.
Image integrity issues create new headache for subarachnoid hemorrhage research
First-time sleuths found potentially problematic images in hundreds of papers about early brain injury after subarachnoid hemorrhage.
Ramping up cortical activity in early life sparks autism-like behaviors in mice
The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.
Ramping up cortical activity in early life sparks autism-like behaviors in mice
The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.