Pain
Recent articles
Immune cells block pain in female mice only
Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.

Immune cells block pain in female mice only
Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.
Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’
In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.

The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’
In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.
UBE3A’s link to synaptic pruning bolstered by fly study
Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.

UBE3A’s link to synaptic pruning bolstered by fly study
Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.
Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring
This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.

Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring
This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.
On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.

On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.
Pain keeps autistic women and girls home from work, school
More autistic women and girls report daily pain than do men and boys with the condition.

Pain keeps autistic women and girls home from work, school
More autistic women and girls report daily pain than do men and boys with the condition.
Epidurals linked to slightly higher autism odds, but connection is unclear
Women who receive epidural anesthesia during labor have an elevated chance of having a child with autism, a new study has found. But it is too soon for doctors to recommend against epidurals, experts say.

Epidurals linked to slightly higher autism odds, but connection is unclear
Women who receive epidural anesthesia during labor have an elevated chance of having a child with autism, a new study has found. But it is too soon for doctors to recommend against epidurals, experts say.
Explore more from The Transmitter
Exclusive: Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.

Exclusive: Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.
Chris Rozell explains how brain stimulation and AI are helping to treat mental disorders
Rozell and his colleagues, using deep brain stimulation and explainable artificial intelligence, have developed tools to help people with treatment-resistant depression.
Chris Rozell explains how brain stimulation and AI are helping to treat mental disorders
Rozell and his colleagues, using deep brain stimulation and explainable artificial intelligence, have developed tools to help people with treatment-resistant depression.
This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations
By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.

This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations
By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.