Postmortem brains

Recent articles

Computer-generated images of the human brain showing functional networks.

Cell ‘fingerprints’ identify distinct cortical networks

These networks align with different assemblages of cells, a finding that could reveal how cellular diversity influences brain function, according to a new study.

By Holly Barker
28 February 2025 | 4 min read
Research image showing duplicated images of potential plastic particles in brain tissue.

‘Spoonful of plastics in your brain’ paper has duplicated images

The duplications likely do not alter the conclusions, but the paper contains other methodological issues, two independent microplastics researchers say.

By Calli McMurray
25 February 2025 | 5 min read
Six different neurons.

Early trajectory of Alzheimer’s tracked in single-cell brain atlases

Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.

By Angie Voyles Askham
23 October 2024 | 8 min read
Research illustration groups genes by their effects on brain cell types.

Giant analysis reveals how autism-linked genes affect brain cell types

Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.

By Charles Q. Choi
20 June 2024 | 5 min read
A research image showing astrocytes and neurons

‘SNAP’ dance of astrocytes and neurons falls out of step with age, disease

The findings add to growing evidence that astrocytes are star players in cognition.

By Laura Dattaro
6 March 2024 | 6 min read
Illustration of two neurons with a shared origin point.

Cortical interneurons derive differently in human brains

Excitatory neurons and some inhibitory neurons in the adult human cortex share parents, challenging the longstanding idea that the two cell types have different origins.

By Elissa Welle
20 December 2023 | 6 min read
Research image of various types of cells.

Vast diversity of human brain cell types revealed in trove of new datasets

The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.

By Angie Voyles Askham
12 October 2023 | 7 min listen
Research image of organoids in the forebrain.

Head size parts autism into two major subtypes

An imbalance in the number of excitatory neurons in early brain development may account for the difference.

By Charles Q. Choi
12 September 2023 | 4 min read
A brain slice under a microscope.

Preprint questions validity of postmortem brain studies

But the alternatives, including living-brain biopsies, raise logistical and ethical questions, experts say.

By Katie Moisse
5 June 2023 | 6 min listen
Research diagram of gene clusters.

Atlas of gene activity in prenatal brain holds clues to autism

Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.

By Brendan Borrell
24 April 2023 | 4 min read

Explore more from The Transmitter

Molecular changes after MECP2 loss may drive Rett syndrome traits

Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.

By Chloe Williams
20 March 2025 | 5 min read

Learning scientific rigor: Q&A with Konrad Kording and Hao Ye

The developers of a new open-access curriculum to teach rigor discuss confirmation bias and other common errors in scientific thinking, plus ways to avoid these missteps.

By Calli McMurray
19 March 2025 | 6 min read
Illustration of a woman sitting on a branch with a singing bird.

This paper changed my life: Stephanie Palmer on the ties between human speech and birdsong—and her ‘informal life coach’

A groundbreaking review by Allison Doupe, who was Palmer’s mentor, and Patricia Kuhl helped shape the field’s understanding of the neural and evolutionary dynamics of speech.

By Stephanie Palmer
18 March 2025 | 5 min read