This paper changed my life

Recent articles

Neuroscientists respond to a set of questions to reflect on a paper that profoundly influenced their career and how they think about their research.

This paper changed my life: Victoria Abraira on a tasty link between circuits and behavior

The findings from Charles Zuker’s lab put the taste system on the map, revealing that some fundamental principles of behavior are hardwired.

By Victoria Abraira
22 July 2025 | 5 min listen
Illustration of a fly in various poses.

This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day

This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

By Bradley Dickerson
17 June 2025 | 5 min listen
Conceptual illustration of four heads studying representations of neural mechanisms.

This paper changed my life: Marino Pagan recalls a decision-making study from four titans in the field

Valerio Mante and David Sussillo, along with their mentors Krishna Shenoy and Bill Newsome, revealed the complexity of neural population dynamics and the power of recurrent neural networks.

By Marino Pagan
13 May 2025 | 7 min listen
Illustration of astrocytes in a petri dish.

This paper changed my life: Shane Liddelow on two papers that upended astrocyte research

A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

By Shane Liddelow
23 April 2025 | 7 min listen
Illustration of a woman sitting on a branch with a singing bird.

This paper changed my life: Stephanie Palmer on the ties between human speech and birdsong—and her ‘informal life coach’

A groundbreaking review by Allison Doupe, who was Palmer’s mentor, and Patricia Kuhl helped shape the field’s understanding of the neural and evolutionary dynamics of speech.

By Stephanie Palmer
18 March 2025 | 5 min read
Illustration of columns of text with eyes peeking out from behind the central column to look at a bright blue spot.

This paper changed my life: Bill Newsome reflects on a quadrilogy of classic visual perception studies

The 1970s papers from Goldberg and Wurtz made ambitious mechanistic studies of higher brain functions seem feasible.

By Bill Newsome
21 February 2025 | 6 min read
Illustration of lines of text being distorted by red orbs.

This paper changed my life: ‘A massively parallel architecture for a self-organizing neural pattern recognition machine,’ by Carpenter and Grossberg

This paper taught me that we can use mathematical modeling to understand how neural networks are organized—and led me to a doctoral program in the department led by its authors.

By Luiz Pessoa
6 January 2025 | 3 min read
Illustration of a pen hovering over a gene sequence-like series of colored rectangles.

This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab

This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.

By Anne E. West
27 November 2024 | 5 min read
Illustration of three columns of text with certain passages underlined and circled.

This paper changed my life: ‘Spontaneous cortical activity reveals hallmarks of an optimal internal model of the environment,’ from the Fiser Lab

Fiser’s work taught me how to think about grounding computational models in biologically plausible implementations.

By Megan Peters
16 October 2024 | 6 min listen
Illustration of a brain.

This paper changed my life: ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens

The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.

By Robert Froemke
17 September 2024 | 4 min read

Explore more from The Transmitter

New dopamine sensor powers three-color imaging in live animals

The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

By Diana Kwon
25 July 2025 | 5 min listen

Cell ‘antennae’ link autism, congenital heart disease

Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.

By Lauren Schenkman
24 July 2025 | 4 min listen
Illustration of people collaborating in different locations.

How to build a truly global computational neuroscience community

Computational sciences offer an opportunity to increase global access to, and participation in, neuroscience. Neuromatch’s inclusive, scalable model for community building shows how to realize this promise.

By Megan Peters, Bradley Roberts
23 July 2025 | 9 min listen