This paper changed my life
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Neuroscientists respond to a set of questions to reflect on a paper that profoundly influenced their career and how they think about their research.
This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle
In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work taught me that these aren’t just passive containers for neurotransmitters but dynamic, precision-built nanomachines.

This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle
In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work taught me that these aren’t just passive containers for neurotransmitters but dynamic, precision-built nanomachines.
This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks
Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.

This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks
Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.
This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations
By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.

This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations
By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.
This paper changed my life: Victoria Abraira on a tasty link between circuits and behavior
The findings from Charles Zuker’s lab put the taste system on the map, revealing that some fundamental principles of behavior are hardwired.

This paper changed my life: Victoria Abraira on a tasty link between circuits and behavior
The findings from Charles Zuker’s lab put the taste system on the map, revealing that some fundamental principles of behavior are hardwired.
This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day
This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day
This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.
This paper changed my life: Marino Pagan recalls a decision-making study from four titans in the field
Valerio Mante and David Sussillo, along with their mentors Krishna Shenoy and Bill Newsome, revealed the complexity of neural population dynamics and the power of recurrent neural networks.

This paper changed my life: Marino Pagan recalls a decision-making study from four titans in the field
Valerio Mante and David Sussillo, along with their mentors Krishna Shenoy and Bill Newsome, revealed the complexity of neural population dynamics and the power of recurrent neural networks.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
This paper changed my life: Stephanie Palmer on the ties between human speech and birdsong—and her ‘informal life coach’
A groundbreaking review by Allison Doupe, who was Palmer’s mentor, and Patricia Kuhl helped shape the field’s understanding of the neural and evolutionary dynamics of speech.

This paper changed my life: Stephanie Palmer on the ties between human speech and birdsong—and her ‘informal life coach’
A groundbreaking review by Allison Doupe, who was Palmer’s mentor, and Patricia Kuhl helped shape the field’s understanding of the neural and evolutionary dynamics of speech.
This paper changed my life: Bill Newsome reflects on a quadrilogy of classic visual perception studies
The 1970s papers from Goldberg and Wurtz made ambitious mechanistic studies of higher brain functions seem feasible.

This paper changed my life: Bill Newsome reflects on a quadrilogy of classic visual perception studies
The 1970s papers from Goldberg and Wurtz made ambitious mechanistic studies of higher brain functions seem feasible.
This paper changed my life: ‘A massively parallel architecture for a self-organizing neural pattern recognition machine,’ by Carpenter and Grossberg
This paper taught me that we can use mathematical modeling to understand how neural networks are organized—and led me to a doctoral program in the department led by its authors.

This paper changed my life: ‘A massively parallel architecture for a self-organizing neural pattern recognition machine,’ by Carpenter and Grossberg
This paper taught me that we can use mathematical modeling to understand how neural networks are organized—and led me to a doctoral program in the department led by its authors.
Explore more from The Transmitter
Gene variants accumulate in older men’s sperm; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 20 October.

Gene variants accumulate in older men’s sperm; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 20 October.
Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.

Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.
Fly database secures funding for another year, but future remains in flux
The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.

Fly database secures funding for another year, but future remains in flux
The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.