This paper changed my life

Recent articles

Neuroscientists respond to a set of questions to reflect on a paper that profoundly influenced their career and how they think about their research.

Illustration of ants marching back to an anthill.

This paper changed my life: John Tuthill reflects on the subjectivity of selfhood

Wittlinger, Wehner and Wolf’s 2006 “stilts and stumps” Science paper revealed how ants pull off extraordinary feats of navigation using a biological odometer, and it inspired Tuthill to consider how other insects sense their own bodies.

By John Tuthill
12 January 2026 | 7 min read
Illustration of human figures holding brightly colored connected dots.

The best of ‘this paper changed my life’ in 2025

From a study that upended astrocyte research to one that reignited the field of spiking neural networks, experts weighed in on the papers that significantly shaped how they think about and approach neuroscience.

By The Transmitter
24 December 2025 | 2 min read
Illustration of a group of neurons.

This paper changed my life: Nancy Padilla-Coreano on learning the value of population coding

The 2013 Nature paper by Mattia Rigotti and his colleagues revealed how mixed selectivity neurons—cells that are not selectively tuned to a stimulus—play a key role in cognition.

By Nancy Padilla-Coreano
1 December 2025 | 5 min read
Abstract illustration of a synaptic vesicle.

This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle

In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work taught me that these aren’t just passive containers for neurotransmitters but dynamic, precision-built nanomachines.

By Sandra Jurado
21 October 2025 | 5 min read
Illustration of human figures holding brightly colored connected dots.

This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks

Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.

By Dan Goodman
17 September 2025 | 5 min read
Illustration of a musical staff with notes represented by neurons.

This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations

By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.

By Abigail Person
12 August 2025 | 5 min read
People stand at a conveyor belt that emanates from an open mouth and pick fruit-shaped objects off of it.

This paper changed my life: Victoria Abraira on a tasty link between circuits and behavior

The findings from Charles Zuker’s lab put the taste system on the map, revealing that some fundamental principles of behavior are hardwired.

By Victoria Abraira
22 July 2025 | 4 min read
Illustration of a fly in various poses.

This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day

This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

By Bradley Dickerson
17 June 2025 | 5 min read
Conceptual illustration of four heads studying representations of neural mechanisms.

This paper changed my life: Marino Pagan recalls a decision-making study from four titans in the field

Valerio Mante and David Sussillo, along with their mentors Krishna Shenoy and Bill Newsome, revealed the complexity of neural population dynamics and the power of recurrent neural networks.

By Marino Pagan
13 May 2025 | 6 min read
Illustration of astrocytes in a petri dish.

This paper changed my life: Shane Liddelow on two papers that upended astrocyte research

A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

By Shane Liddelow
23 April 2025 | 6 min read

Explore more from The Transmitter

Prenatal viral injections prime primate brain for study

The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.

By Angie Voyles Askham
22 January 2026 | 5 min read
Researcher Russell Poldrack's face closeup, with a scanner seen out of focus behind him.

A brief history of precision self-scanning

When a researcher solved a logistical problem by going rogue, the idea proved remarkably infectious.

By Lauren Gravitz
21 January 2026 | 14 min read
Pyramidal neurons in the mouse hippocampus.

Sensory profiles in autism, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 19 January.

By Jill Adams
20 January 2026 | 2 min read

privacy consent banner

Privacy Preference

We use cookies to provide you with the best online experience. By clicking “Accept All,” you help us understand how our site is used and enhance its performance. You can change your choice at any time. To learn more, please visit our Privacy Policy.