Molecular neuroscience
Recent articles
New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt
In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community’s “Grand Plan.”

‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt
In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community’s “Grand Plan.”
How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.

The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.
Hessameddin Akhlaghpour outlines how RNA may implement universal computation
Could the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Akhlaghpour describes how natural universal computation may have evolved via RNA mechanisms.
Hessameddin Akhlaghpour outlines how RNA may implement universal computation
Could the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Akhlaghpour describes how natural universal computation may have evolved via RNA mechanisms.
How to be a multidisciplinary neuroscientist
Neuroscience subfields are often siloed. Embracing an integrative approach during training can help change that.

How to be a multidisciplinary neuroscientist
Neuroscience subfields are often siloed. Embracing an integrative approach during training can help change that.
What are mechanisms? Unpacking the term is key to progress in neuroscience
Mechanism is a common and powerful concept, invoked in grant calls and publication guidelines. But scientists use it in different ways, making it difficult to clarify standards in the field. We asked nine scientists to weigh in.

What are mechanisms? Unpacking the term is key to progress in neuroscience
Mechanism is a common and powerful concept, invoked in grant calls and publication guidelines. But scientists use it in different ways, making it difficult to clarify standards in the field. We asked nine scientists to weigh in.
Male and female brains, Proust, and Catherine Dulac
The 2021 Breakthrough Prize winner explains how reading widely shaped her worldview, and discusses the vomeronasal organ.

Male and female brains, Proust, and Catherine Dulac
The 2021 Breakthrough Prize winner explains how reading widely shaped her worldview, and discusses the vomeronasal organ.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.

Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
Explore more from The Transmitter
Oxytocin shapes both mouse mom and pup behavior
Distressed pups emit distinct cries for help, which depend on oxytocin neurons in their hypothalamus.

Oxytocin shapes both mouse mom and pup behavior
Distressed pups emit distinct cries for help, which depend on oxytocin neurons in their hypothalamus.
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.

Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
Michael Breakspear and Mac Shine explain how brain processing changes across neural population scales
Breakspear and Shine find a scale-free property of brain activity that is conserved across diverse species, suggesting that a universal principle of brain activity underlies cognition.
Michael Breakspear and Mac Shine explain how brain processing changes across neural population scales
Breakspear and Shine find a scale-free property of brain activity that is conserved across diverse species, suggesting that a universal principle of brain activity underlies cognition.