Pain
Recent articles
Immune cells block pain in female mice only
Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.

Immune cells block pain in female mice only
Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.
Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’
In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.

The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’
In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.
UBE3A’s link to synaptic pruning bolstered by fly study
Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.

UBE3A’s link to synaptic pruning bolstered by fly study
Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.
Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring
This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.

Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring
This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.
On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.
On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.
Pain keeps autistic women and girls home from work, school
More autistic women and girls report daily pain than do men and boys with the condition.

Pain keeps autistic women and girls home from work, school
More autistic women and girls report daily pain than do men and boys with the condition.
Epidurals linked to slightly higher autism odds, but connection is unclear
Women who receive epidural anesthesia during labor have an elevated chance of having a child with autism, a new study has found. But it is too soon for doctors to recommend against epidurals, experts say.

Epidurals linked to slightly higher autism odds, but connection is unclear
Women who receive epidural anesthesia during labor have an elevated chance of having a child with autism, a new study has found. But it is too soon for doctors to recommend against epidurals, experts say.
Explore more from The Transmitter
Altered visual processing in a mouse model of fragile X syndrome; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 16 June.

Altered visual processing in a mouse model of fragile X syndrome; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 16 June.
This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day
This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day
This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.
NIH cuts quash $323 million for neuroscience research and training
“I am frightened for the state of the future of our field if this isn't reversed rapidly,” says Joshua Gordon, professor of psychiatry at Columbia University and former director of the National Institute of Mental Health.

NIH cuts quash $323 million for neuroscience research and training
“I am frightened for the state of the future of our field if this isn't reversed rapidly,” says Joshua Gordon, professor of psychiatry at Columbia University and former director of the National Institute of Mental Health.