Postmortem brains

Recent articles

Two slides feature human brains, with a third slide featuring the silhouette of a brain.

Exclusive: Recruitment issues jeopardize ambitious plan for human brain atlas

A lack of six new brain donors may stop the project from meeting its goal to pair molecular and cellular data with the functional organization of the cortex.

By Calli McMurray
9 May 2025 | 6 min listen
fMRI scans exiting a grain silo.

To make a meaningful contribution to neuroscience, fMRI must break out of its silo

We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

By Avram Holmes
8 April 2025 | 8 min listen
Research image of cell types in the human brain.

Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology

Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.

By Ed Lein, Hongkui Zeng
24 March 2025 | 7 min read
Computer-generated images of the human brain showing functional networks.

Cell ‘fingerprints’ identify distinct cortical networks

These networks align with different assemblages of cells, a finding that could reveal how cellular diversity influences brain function, according to a new study.

By Holly Barker
28 February 2025 | 4 min read
Research image showing duplicated images of potential plastic particles in brain tissue.

‘Spoonful of plastics in your brain’ paper has duplicated images

The duplications likely do not alter the conclusions, but the paper contains other methodological issues, two independent microplastics researchers say.

By Calli McMurray
25 February 2025 | 5 min read
Six different neurons.

Early trajectory of Alzheimer’s tracked in single-cell brain atlases

Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.

By Angie Voyles Askham
23 October 2024 | 8 min read
Research illustration groups genes by their effects on brain cell types.

Giant analysis reveals how autism-linked genes affect brain cell types

Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.

By Charles Q. Choi
20 June 2024 | 5 min read
A research image showing astrocytes and neurons

‘SNAP’ dance of astrocytes and neurons falls out of step with age, disease

The findings add to growing evidence that astrocytes are star players in cognition.

By Laura Dattaro
6 March 2024 | 6 min read
Illustration of two neurons with a shared origin point.

Cortical interneurons derive differently in human brains

Excitatory neurons and some inhibitory neurons in the adult human cortex share parents, challenging the longstanding idea that the two cell types have different origins.

By Elissa Welle
20 December 2023 | 6 min read
Research image of various types of cells.

Vast diversity of human brain cell types revealed in trove of new datasets

The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.

By Angie Voyles Askham
12 October 2023 | 7 min listen

Explore more from The Transmitter

Brain scan with visual noise and glitch effects.

Authors retract Science paper on controversial fMRI method

Several known but usually negligible MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted earlier this month.

By Calli McMurray
25 September 2025 | 6 min read
Portrait photograph of Dame Stephanie Shirley.

In memoriam: Stephanie “Steve” Shirley, autism philanthropist

Fueled by business success and her son, she played an outsized role in British autism research.

By Lauren Schneider
25 September 2025 | 6 min read

Ann Kennedy explains the theoretical neuroscience of survival behaviors

The Scripps neuroscientist calls for a broader theoretical neuroscience approach in her area of research, which focuses on how the subcortex bridges life and cognition.

By Paul Middlebrooks
24 September 2025 | 1 min read

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