Theories of autism
Recent articles
The signaling imbalance theory of autism, explained
The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.

The signaling imbalance theory of autism, explained
The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.
The female protective effect, explained
One of the leading theories of autism posits that girls and women are biologically protected from the condition.

The female protective effect, explained
One of the leading theories of autism posits that girls and women are biologically protected from the condition.
The extreme male brain, explained
The ‘extreme male brain’ theory suggests that autism is an exaggeration of systematic sex differences in ways of thinking.

The extreme male brain, explained
The ‘extreme male brain’ theory suggests that autism is an exaggeration of systematic sex differences in ways of thinking.
Serotonin’s link to autism, explained
Serotonin, the brain chemical best known for its link to depression, may also be involved in autism.

Serotonin’s link to autism, explained
Serotonin, the brain chemical best known for its link to depression, may also be involved in autism.
The multiple hits theory of autism, explained
Researchers are studying how a combination of genetic ‘hits’ may contribute to autism’s diversity.

The multiple hits theory of autism, explained
Researchers are studying how a combination of genetic ‘hits’ may contribute to autism’s diversity.
The predictive coding theory of autism, explained
In autism, a person's brain may not form accurate predictions of imminent experiences, or even if it does, sensory input may override those predictions.

The predictive coding theory of autism, explained
In autism, a person's brain may not form accurate predictions of imminent experiences, or even if it does, sensory input may override those predictions.
The connectivity theory of autism, explained
A growing body of evidence suggests that autism involves atypical communication between brain regions, but how and where in the brain this plays out is unclear.

The connectivity theory of autism, explained
A growing body of evidence suggests that autism involves atypical communication between brain regions, but how and where in the brain this plays out is unclear.
Explore more from The Transmitter
Null and Noteworthy: Neurons tracking sequences don’t fire in order
Instead, neurons encode the position of sequential items in working memory based on when they fire during ongoing brain wave oscillations—a finding that challenges a long-standing theory.

Null and Noteworthy: Neurons tracking sequences don’t fire in order
Instead, neurons encode the position of sequential items in working memory based on when they fire during ongoing brain wave oscillations—a finding that challenges a long-standing theory.
How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)
Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.

How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)
Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.
Astrocytes sense neuromodulators to orchestrate neuronal activity and shape behavior
Astrocytes serve as crucial mediators of neuromodulatory processes previously attributed to direct communication between neurons, four new studies show.

Astrocytes sense neuromodulators to orchestrate neuronal activity and shape behavior
Astrocytes serve as crucial mediators of neuromodulatory processes previously attributed to direct communication between neurons, four new studies show.