Anxiety

Image of the dorsal raphe area of the brain.

Neurotransmitter switch-up helps fan extreme stress into full-blown fear

The flip occurs when certain neurons in the dorsal raphe start to express the chemical GABA instead of glutamate, a new study shows.

By Claudia López Lloreda
9 April 2024 | 5 min read
Research image of microglia in rats.

Temperament is innate but hackable, animal studies suggest

Emotional reactivity and vulnerability to stress are largely inherited in rodents — but can be modified in early life by targeting inflammation-related cells or even just adjusting an animal’s environment.

By Holly Barker
23 January 2024 | 8 min read
Three groups of people meet and mix at a crossroads.

Year in Review: Spectrum’s best in 2023

Here are five must-reads from our coverage of autism research over the past 12 months.

28 December 2023 | 4 min read

Autism research hits the road

Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.

By Giorgia Guglielmi
8 December 2023 | 0 min watch
A person stands in front of a neatly organized dresser drawer.

Teasing apart insistence on sameness with Mirko Uljarević

The hallmark autism trait has multiple facets, Uljarević and his colleagues have found.

By Lauren Schenkman
30 October 2023 | 6 min read
A young boy sits alone on a bench in a playground.

Mental health issues emerge with shifts in autism traits across childhood

Anxiety and other challenges autistic children experience may stem from an increase in social-communication issues and a decrease in repetitive behaviors from ages 6 to 11.

By Charles Q. Choi
27 September 2023 | 3 min read
Photograph of a doctor and nurse checking a patient’s temperature and taking notes.
Spectrum Microphone

Co-occurring conditions in autistic teens increase with age

The most prevalent conditions include obesity, neurological disorders, anxiety and attention-deficit/hyperactivity disorder.

By Calli McMurray
8 August 2023 | 1 min read

‘wildDISCO’ cocktail yields whole-body maps of mouse neurons and more

A new technique used to create see-through rodents can help scientists analyze how the nervous system interacts with other body systems.

By Charles Q. Choi
20 July 2023 | 4 min read
A young girl sits on the couch biting her thumb.

Children with autism and ADHD often have additional mental health conditions

The dual diagnosis frequently co-occurs with anxiety, depression and developmental and language delays.

By Maaisha Osman
10 February 2023 | 2 min read
A white mouse, brown mouse and black mouse stand inside a wooden circle against a blue background.
Spectrum Microphone

CHD8 mutation in 33 mouse strains yields range of traits

The findings put genetic background forward to help explain autism’s heterogeneity.

By Peter Hess
3 February 2023 | 5 min read

Explore more from The Transmitter

Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
Illustration of researchers talking to laypeople amidst strands of DNA.

Building an autism research registry: Q&A with Tony Charman

A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.

By Cathleen O’Grady
25 July 2024 | 8 min read

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read