Bioinformatics
Recent articles
Simply making data publicly available isn’t enough. We need to make it easy — that requires community buy-in.
I helped create a standard to make it easy to upload, analyze and compare functional MRI data. An ecosystem of tools has since grown up around it, boosting reproducibility and speeding up research.
Simply making data publicly available isn’t enough. We need to make it easy — that requires community buy-in.
I helped create a standard to make it easy to upload, analyze and compare functional MRI data. An ecosystem of tools has since grown up around it, boosting reproducibility and speeding up research.
Gut microbiome meta-analysis reveals consistent autism signal
But the field needs to move on from cross-sectional studies to gain insights into the causes and consequences of the association, experts say.
Gut microbiome meta-analysis reveals consistent autism signal
But the field needs to move on from cross-sectional studies to gain insights into the causes and consequences of the association, experts say.
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
Africa’s genomic role: Q&A with Conrad Iyegbe and Niran Okewole
Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.
Africa’s genomic role: Q&A with Conrad Iyegbe and Niran Okewole
Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.
‘Dosage sensitivity map’ predicts active ingredients in copy number variants
The catalog of rare copy number variants tied to autism and other conditions could help researchers identify which genes account for the mutations’ effects.
‘Dosage sensitivity map’ predicts active ingredients in copy number variants
The catalog of rare copy number variants tied to autism and other conditions could help researchers identify which genes account for the mutations’ effects.
Lumping versus splitting with autism-linked variants: A conversation with Vanessa Vogel-Farley and Yssa DeWoody
Researchers have long studied subgroups of people who share genetic variants, but the newly formed ‘CNV Commission’ is also looking at people with shared traits across different neurodevelopmental conditions.
Lumping versus splitting with autism-linked variants: A conversation with Vanessa Vogel-Farley and Yssa DeWoody
Researchers have long studied subgroups of people who share genetic variants, but the newly formed ‘CNV Commission’ is also looking at people with shared traits across different neurodevelopmental conditions.
Meet the company trying precision medicine for autism
Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.
Meet the company trying precision medicine for autism
Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.
Alternate RNA versions of genes may shape autism
Autism may involve different levels of RNA isoforms encoded by genes in the brain, which express many more proteins than previously thought.
Alternate RNA versions of genes may shape autism
Autism may involve different levels of RNA isoforms encoded by genes in the brain, which express many more proteins than previously thought.
Protein atlas doubles number of known interactions in mice
Thousands of protein-protein interactions mapped in mice reveal how these networks shift across seven kinds of tissue.
Protein atlas doubles number of known interactions in mice
Thousands of protein-protein interactions mapped in mice reveal how these networks shift across seven kinds of tissue.
Ultra-rare variants point to new autism candidate genes
A large, whole-genome sequencing study of families yields insights into ultra-rare genetic variants that contribute to autism.
Ultra-rare variants point to new autism candidate genes
A large, whole-genome sequencing study of families yields insights into ultra-rare genetic variants that contribute to autism.
Explore more from The Transmitter
Trading places: What happens when neuroscience turns into machine learning, and machine learning turns into neuroscience?
Neuroscience has become increasingly concerned with prediction, and machine learning with causal explanation, with each field adopting methods from the other. I asked eight experts to weigh in on what we stand to learn from this exchange.
Trading places: What happens when neuroscience turns into machine learning, and machine learning turns into neuroscience?
Neuroscience has become increasingly concerned with prediction, and machine learning with causal explanation, with each field adopting methods from the other. I asked eight experts to weigh in on what we stand to learn from this exchange.
Exon-skipping approach boosts levels of key Rett syndrome protein
Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.
Exon-skipping approach boosts levels of key Rett syndrome protein
Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.
Frameshift: How Caitlin Vander Weele made science communication her business
Her favorite part of research was talking about it. So she left academia and turned that passion into a successful company.
Frameshift: How Caitlin Vander Weele made science communication her business
Her favorite part of research was talking about it. So she left academia and turned that passion into a successful company.