Dopamine
Recent articles
‘What Is Intelligence?’: An excerpt
In his new book, published today, Blaise Agüera y Arcas examines the fundamental aspects of intelligence in biological and artificial systems. In this excerpt from Chapter 4, he examines temporal difference, a reinforcement learning algorithm.

‘What Is Intelligence?’: An excerpt
In his new book, published today, Blaise Agüera y Arcas examines the fundamental aspects of intelligence in biological and artificial systems. In this excerpt from Chapter 4, he examines temporal difference, a reinforcement learning algorithm.
New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
Large study links autism to Parkinson’s disease
Autistic adults appear to be prone to an early-onset form of Parkinson’s, according to a long-term study that tracked 2.2 million people in Sweden.

Large study links autism to Parkinson’s disease
Autistic adults appear to be prone to an early-onset form of Parkinson’s, according to a long-term study that tracked 2.2 million people in Sweden.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.

Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.
Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control
The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.

Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control
The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.
The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.

The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.
In case you missed it: Standout news stories from 2024
These five stories—on the pregnant brain, a failed imaging method and more—top our list of some of the most notable neuroscience research findings this year.

In case you missed it: Standout news stories from 2024
These five stories—on the pregnant brain, a failed imaging method and more—top our list of some of the most notable neuroscience research findings this year.
Vijay Namboodiri and Ali Mohebi on the evolving story of dopamine’s role in cognitive function
Researchers discuss the classic stories of dopamine’s role in learning, ongoing work linking it to a wide variety of cognitive functions, and recent research suggesting that dopamine may help us "look back" to discover the causes of events in the world.
Vijay Namboodiri and Ali Mohebi on the evolving story of dopamine’s role in cognitive function
Researchers discuss the classic stories of dopamine’s role in learning, ongoing work linking it to a wide variety of cognitive functions, and recent research suggesting that dopamine may help us "look back" to discover the causes of events in the world.
Explore more from The Transmitter
Meet the Autism Data Science Initiative grantees
The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.

Meet the Autism Data Science Initiative grantees
The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.
Exclusive: The 23 studies the FDA based its expanded leucovorin label on
The studies include 46 people, mostly toddlers, who have cerebral folate deficiency due to variants in a folate transporter.

Exclusive: The 23 studies the FDA based its expanded leucovorin label on
The studies include 46 people, mostly toddlers, who have cerebral folate deficiency due to variants in a folate transporter.
Autism researchers ‘pleasantly surprised’ by list of NIH data project grantees, despite initial concerns
An atypical funding mechanism, truncated application timeline and opaque review process had generated concern over the quality of projects that would be selected for the Autism Data Science Initiative.

Autism researchers ‘pleasantly surprised’ by list of NIH data project grantees, despite initial concerns
An atypical funding mechanism, truncated application timeline and opaque review process had generated concern over the quality of projects that would be selected for the Autism Data Science Initiative.