Dopamine
Recent articles
This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments
In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.
This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments
In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.
Sex hormone boosts female rats’ sensitivity to unexpected rewards
During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.
Sex hormone boosts female rats’ sensitivity to unexpected rewards
During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.
‘What Is Intelligence?’: An excerpt
In his new book, published today, Blaise Agüera y Arcas examines the fundamental aspects of intelligence in biological and artificial systems. In this excerpt from Chapter 4, he examines temporal difference, a reinforcement learning algorithm.
‘What Is Intelligence?’: An excerpt
In his new book, published today, Blaise Agüera y Arcas examines the fundamental aspects of intelligence in biological and artificial systems. In this excerpt from Chapter 4, he examines temporal difference, a reinforcement learning algorithm.
New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
Large study links autism to Parkinson’s disease
Autistic adults appear to be prone to an early-onset form of Parkinson’s, according to a long-term study that tracked 2.2 million people in Sweden.
Large study links autism to Parkinson’s disease
Autistic adults appear to be prone to an early-onset form of Parkinson’s, according to a long-term study that tracked 2.2 million people in Sweden.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.
Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.
Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control
The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.
Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control
The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.
The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.
The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.
Explore more from The Transmitter
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
Leucovorin, long-read sequencing, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 16 March.
Leucovorin, long-read sequencing, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 16 March.
Large-scale neuroimaging datasets often lack information specific to women’s health, constraining AI’s analysis potential
Addressing this gap will require collecting widespread data on pregnancy, menopause and other life events women experience—and could bring us closer to the “holy grail” of linking brain and behavior.
Large-scale neuroimaging datasets often lack information specific to women’s health, constraining AI’s analysis potential
Addressing this gap will require collecting widespread data on pregnancy, menopause and other life events women experience—and could bring us closer to the “holy grail” of linking brain and behavior.