Neuroinflammation
Recent articles
How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)
Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.

How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)
Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.
Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease
To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.

Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease
To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
Unexpected astrocyte gene flips image of brain’s ‘stalwart sentinels’
The genetic marker upends the accepted orientation of non-star-like astrocytes in the glia limitans superficialis.

Unexpected astrocyte gene flips image of brain’s ‘stalwart sentinels’
The genetic marker upends the accepted orientation of non-star-like astrocytes in the glia limitans superficialis.
Rethinking mental health: The body’s impact on the brain
Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.

Rethinking mental health: The body’s impact on the brain
Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.
Age-related brain changes in mice strike hypothalamus ‘hot spot’
Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.

Age-related brain changes in mice strike hypothalamus ‘hot spot’
Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.
Immune cell interlopers breach—and repair—brain barrier in mice
The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.

Immune cell interlopers breach—and repair—brain barrier in mice
The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.
Mouse housing temperatures can cook experimental outcomes
Neuroscientists need to take note of how thermoregulatory processes influence the brain and behavior—for the sake of reproducibility and animal welfare.

Mouse housing temperatures can cook experimental outcomes
Neuroscientists need to take note of how thermoregulatory processes influence the brain and behavior—for the sake of reproducibility and animal welfare.
Temperament is innate but hackable, animal studies suggest
Emotional reactivity and vulnerability to stress are largely inherited in rodents — but can be modified in early life by targeting inflammation-related cells or even just adjusting an animal’s environment.

Temperament is innate but hackable, animal studies suggest
Emotional reactivity and vulnerability to stress are largely inherited in rodents — but can be modified in early life by targeting inflammation-related cells or even just adjusting an animal’s environment.
Explore more from The Transmitter
Robots marry natural neuroscience, experimental control to probe animal interactions
Faux fish and birds are helping researchers decipher some of the rules that govern schooling and squawking, among other social behaviors.

Robots marry natural neuroscience, experimental control to probe animal interactions
Faux fish and birds are helping researchers decipher some of the rules that govern schooling and squawking, among other social behaviors.
Long-read sequencing unearths overlooked autism-linked variants
Strips that are thousands of base pairs in length offer better resolution of structural variants and tandem repeats, according to two independent preprints.

Long-read sequencing unearths overlooked autism-linked variants
Strips that are thousands of base pairs in length offer better resolution of structural variants and tandem repeats, according to two independent preprints.
Competition seeks new algorithms to classify social behavior in animals
The winner of the competition, which launched today and tests contestants’ models head to head, is set to take home $20,000, according to co-organizer Ann Kennedy.

Competition seeks new algorithms to classify social behavior in animals
The winner of the competition, which launched today and tests contestants’ models head to head, is set to take home $20,000, according to co-organizer Ann Kennedy.