Open-source tools

Recent articles

A crumpled sheet of paper with a fly printed on it.

FlyBase funding squashed amid Harvard grant terminations

The team behind the Drosophila genetics database is now requesting donations from labs to keep the resource afloat.

By Calli McMurray
4 June 2025 | 4 min read
Photograph of the BRIDGE team and students visiting a laboratory.

Sharing Africa’s brain data: Q&A with Amadi Ihunwo

These data are “virtually mandatory” to advance neuroscience, says Ihunwo, a co-investigator of the Brain Research International Data Governance & Exchange (BRIDGE) initiative, which seeks to develop a global framework for sharing, using and protecting neuroscience data.

By Lauren Schenkman
20 May 2025 | 6 min read
A young child in a blue shirt sits in a red chair and speaks to an adult at the edge of the frame.

AI tool estimates social ability by analyzing speech

The system’s code and training data—drawn from one of the largest databases of speech recordings from autistic people—are openly available.

By Charles Q. Choi
13 February 2025 | 5 min read
Illustration of three figures standing in front of a grid of dots and a world map.

The S-index Challenge: Develop a metric to quantify data-sharing success

The NIH-sponsored effort aims to help incentivize scientists to share data. But many barriers to the widespread adoption of useful data-sharing remain.

By Loren Frank
8 October 2024 | 6 min listen
Research image of a variety of brain atlases.

New ‘decoder’ tool translates functional neuroimaging terms across labs

The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.

By Holly Barker
23 July 2024 | 4 min read
Research image of data from electrode arrays inserted into mice.

10 standards for brain electrode-array recordings enhance reproducibility

Electrophysiology findings can vary widely from lab to lab, even among those using identical protocols. New guidelines set forth in a preprint should help.

By Elissa Welle
12 July 2024 | 5 min read
Image of neural activity in a mouse as seen through the Miniscope.

Designing an open-source microscope

Funding for the development of open-source tools is on the rise, but support for their maintenance and dissemination, both crucial for their meaningful uptake, remains a major challenge.

By Daniel Aharoni
17 June 2024 | 6 min read

Getting musical to spot patterns in whole-brain imaging data: Q&A with Elizabeth Hillman

The new technique takes advantage of humans’ “extraordinary” sensory processing abilities, Hillman says.

By Calli McMurray
21 February 2024 | 0 min watch

Explore more from The Transmitter

On the importance of reading (just not too much)

The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.

By Sheena Josselyn
9 June 2025 | 8 min read
Research image of developing axons in the fly brain.

How developing neurons simplify their search for a synaptic mate

Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

By Calli McMurray
6 June 2025 | 6 min read
Distorted floppy discs.

NIH autism database announcement raises concerns among researchers

The U.S. National Institutes of Health announced a plan to pour $50 million into data science projects intended to investigate the condition’s causes, but the initiative’s short timeline and other atypicalities have prompted questions.

By Angie Voyles Askham
5 June 2025 | 5 min read